Cosentino Claudia, Rossi Eleonora, Pala Laura, Lelmi Romina, Campanino Chiara, Ricca Valdo, Mannucci Edoardo, Dicembrini Ilaria, Rotella Francesco
Diabetology Unit, Pistoia San Jacopo Hospital, Pistoia, Italy.
Psychiatry Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Acta Diabetol. 2023 May;60(5):681-686. doi: 10.1007/s00592-023-02044-9. Epub 2023 Feb 20.
Orthorexia nervosa (ON) is a condition characterized by an excessive importance attributed to the intake of healthy foods. This study was aimed at investigating the prevalence of ON in subjects with type 1 diabetes (T1D) compared to control subjects.
Patient with T1D using either flash glucose monitoring or continuous glucose monitoring were enrolled. For the selection of control group, each patient was asked to indicate one non-diabetic subject of their same sex and approximate age among colleagues at work and school. Patients and controls completed the following questionnaires: ORTO-15, Dusseldorf Orthorexie Scale (DOS), Eating Disorder Examination Questionnaire (EDE-Q) and Brief Symptom Inventory (BSI). The principal outcome was the prevalence of ON among T1D and control subjects.
We enrolled 44 patients with T1D aged 39.7 ± 15.7 years, with BMI 24.3 ± 4.3 kg/m, and mean HbA1c 53.5 [49-57] mmol/mol. Control subjects were similar to T1D with respect to sex, age and BMI. Thirty-two [72%] and 29 [65%] subjects among patients and controls, respectively, had ORTO15 < 40 (between-group p = 0.48). Two (4.5%) and zero subjects among patients and controls, respectively, had DOS ≥ 30 (p = 0.29). Median scores of DOS, but not of ORTO-15, were significantly higher in patients than in controls. None of the metabolic variables showed a correlation with psychometric tests in T1D.
Although the prevalence of ON was not significantly higher in T1D than in controls, patients with T1D showed higher scores of some, but not all, tests assessing orthorexia, without any significant correlation with metabolic parameters.
神经性正食症（ON）是一种以过度重视健康食品摄入为特征的病症。本研究旨在调查1型糖尿病（T1D）患者与对照受试者中ON的患病率。
纳入使用闪光葡萄糖监测或持续葡萄糖监测的T1D患者。为选择对照组，要求每位患者在同事和同学中指出一名与自己性别相同、年龄相近的非糖尿病受试者。患者和对照者完成以下问卷：ORTO - 15、杜塞尔多夫正食症量表（DOS）、饮食失调检查问卷（EDE - Q）和简明症状量表（BSI）。主要结果是T1D患者和对照受试者中ON的患病率。
我们纳入了44例年龄为39.7±15.7岁的T1D患者，BMI为24.3±4.3kg/m²，平均糖化血红蛋白为53.5[49 - 57]mmol/mol。对照受试者在性别、年龄和BMI方面与T1D患者相似。患者组和对照组中分别有32例（72%）和29例（65%）受试者的ORTO15＜40（组间p = 0.48）。患者组和对照组中分别有2例（4.5%）和0例受试者的DOS≥30（p = 0.29）。患者的DOS中位数得分显著高于对照组，但ORTO - 15的中位数得分并非如此。在T1D患者中，没有任何代谢变量与心理测量测试相关。
尽管T1D患者中ON的患病率并不显著高于对照组，但T1D患者在一些（而非全部）评估正食症的测试中得分较高，且与代谢参数无任何显著相关性。
