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痉挛评估和管理工具。

Spasticity evaluation and management tools.

机构信息

Rehabilitation Care Services, Veterans Affairs Sound, Seattle, Washington, DC, USA.

Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.

出版信息

Muscle Nerve. 2023 Apr;67(4):272-283. doi: 10.1002/mus.27792. Epub 2023 Feb 19.

Abstract

Spasticity is a complex and often disabling symptom for patients with upper motor neuron syndromes. Although spasticity arises from neurological disease, it often cascades into muscle and soft tissue changes, which may exacerbate symptoms and further hamper function. Effective management therefore hinges on early recognition and treatment. To this end, the definition of spasticity has expanded over time to more accurately reflect the spectrum of symptoms experienced by persons with this disorder. Once identified, clinical and research quantitative assessments of spasticity are hindered by the uniqueness of presentations both for individuals and for specific neurological diagnoses. Objective measures in isolation often fail to reflect the complex functional impact of spasticity. Multiple tools exist to quantitatively or qualitatively assess the severity of spasticity, including clinician and patient-reported measures as well as electrodiagnostic, mechanical, and ultrasound measures. A combination of objective and patient-reported outcomes is likely required to better reflect the burden of spasticity symptoms in an individual. Therapeutic options exist for the treatment of spasticity along a broad spectrum from nonpharmacologic to interventional procedures. Treatment strategies may include exercise, physical agent modalities, oral medications, injections, pumps, and surgery. Optimal spasticity management most often requires a multimodal approach, combining pharmacological management with interventions that match the functional needs, goals, and preferences of the patient. Physicians and other healthcare providers who manage spasticity must be familiarized with the full array of spasticity interventions and must frequently reassess results of treatment to ensure the patient's goals of treatment are met.

摘要

痉挛是上运动神经元综合征患者的一种复杂且常导致残疾的症状。尽管痉挛是由神经系统疾病引起的,但它常常会引发肌肉和软组织的变化,从而加重症状并进一步妨碍功能。因此,有效的管理取决于早期识别和治疗。为此,痉挛的定义随着时间的推移而扩大,以更准确地反映患有这种疾病的人的症状谱。一旦确定,痉挛的临床和研究定量评估受到个体和特定神经诊断呈现的独特性的阻碍。单独的客观测量往往无法反映痉挛的复杂功能影响。存在多种工具可用于定量或定性评估痉挛的严重程度,包括临床医生和患者报告的措施以及电诊断、机械和超声措施。为了更好地反映个体痉挛症状的负担,可能需要结合客观和患者报告的结果。存在广泛的治疗痉挛的选择,从非药物到介入性手术。治疗策略可能包括运动、物理因子疗法、口服药物、注射、泵和手术。最佳的痉挛管理通常需要多模式方法,将药物管理与符合患者功能需求、目标和偏好的干预措施相结合。管理痉挛的医生和其他医疗保健提供者必须熟悉所有痉挛干预措施,并经常重新评估治疗结果,以确保满足患者的治疗目标。

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