Department of Chemistry (Centre of Advanced Study), Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
Environ Sci Pollut Res Int. 2023 Apr;30(18):54250-54251. doi: 10.1007/s11356-023-26015-3. Epub 2023 Feb 20.
This is an answer to the letter by the editor that was sent in response to our previously published article entitled "Voltammetric analysis of epinephrine using glassy carbon electrode modified with nanocomposite prepared from Co-Nd bimetallic nanoparticles, alumina nanoparticles and functionalized multiwalled carbon nanotubes." We are grateful to the writers for showing an interest in our manuscript and for providing such helpful feedback. We emphasise that our research was just a preliminary investigation to detect epinephrine in different biological samples, however, in literature a link between epinephrine and acute respiratory distress syndrome (ARDS) is already reported. Hence, we are agreeing to the authors that epinephrine is suggested as a cause for ARDS following anaphylaxis. It is recommended that more research be carried out to evaluate the possibility of epinephrine as a cause for ARDS and to validate the therapeutic relevance of the findings. Additionally, the purpose of our research was electrochemical sensing of epinephrine alternative to the conventional means like HPLC, fluorimetry, etc. for epinephrine detection. We have found that benefits which the electrochemical sensors have, are their simplicity, cost-effectiveness, ease of use owing to their small size, mass manufacture, and straightforward operation, as well as their extreme sensitivity and selectivity, hence the electrochemical sensing methods are more beneficial than conventional techniques for epinephrine analysis.
这是对编辑来信的回复,该信是对我们之前发表的题为“使用由 Co-Nd 双金属纳米粒子、氧化铝纳米粒子和功能化多壁碳纳米管制备的纳米复合材料修饰的玻碳电极对肾上腺素进行伏安分析”的文章的回应。我们感谢作者对我们的手稿表现出兴趣,并提供了如此有帮助的反馈。我们强调,我们的研究只是初步调查,以检测不同生物样本中的肾上腺素,然而,文献中已经报道了肾上腺素与急性呼吸窘迫综合征(ARDS)之间的联系。因此,我们同意作者的观点,即肾上腺素被认为是过敏反应后 ARDS 的一个原因。建议进行更多的研究,以评估肾上腺素作为 ARDS 原因的可能性,并验证这些发现的治疗相关性。此外,我们的研究目的是用电化学传感器替代传统方法(如 HPLC、荧光法等)来检测肾上腺素。我们已经发现,电化学传感器具有以下优势:简单、经济实惠、易于使用(由于其体积小、大规模制造和简单的操作),以及极高的灵敏度和选择性,因此电化学传感方法比传统技术更有利于肾上腺素分析。