Department of Radiology, Emergency County Hospital Sibiu, Romania;
Rom J Morphol Embryol. 2022 Oct-Dec;63(4):653-657. doi: 10.47162/RJME.63.4.08.
Solitary fibrous tumor (SFT) of the breast is a rare mesenchymal tumor composed of spindle-shaped tumor cells with collagen and large blood vessels in the shape of a "staghorn". It is discovered anywhere in the human body, usually incidentally or through nonspecific symptoms. A combination of clinical, histological, and immunohistochemical features is required to establish a diagnosis. There are no proper guidelines for the treatment of SFTs because of their rarity; however, wide surgical excision remains the "gold standard". A multidisciplinary team approach is recommended. They are mostly benign with a 5-year survival rate of 89%. Following a PubMed-indexed English literature review, only six publications presenting nine cases of breast SFT in a male patient were found. The following is the case of a 73-year-old man who presented with dry cough. A SFT in the right breast was discovered incidentally during the investigative work up, and the patient was referred to our Breast Clinic at the Jules Bordet Institute, Brussels, Belgium, for appropriate treatment. The patient's presentation, imaging, and histological sample all supported the diagnosis, and he underwent uneventful surgical resection. Here, we present the first case of an incidental finding of a SFT of the male breast, with its diagnosis and therapeutic challenges.
乳腺孤立性纤维瘤（SFT）是一种罕见的间叶性肿瘤，由梭形肿瘤细胞组成，呈“鹿角状”排列，伴有胶原和大血管。它可以在人体任何部位发现，通常是偶然发现或通过非特异性症状发现。需要结合临床、组织学和免疫组织化学特征来建立诊断。由于其罕见性，目前尚无治疗 SFT 的适当指南；然而，广泛的手术切除仍然是“金标准”。建议采用多学科团队方法。它们大多是良性的，5 年生存率为 89%。通过对 PubMed 索引的英文文献进行综述，仅发现了 6 篇发表的关于男性乳腺 SFT 的 9 例病例的出版物。以下是一名 73 岁男性患者的病例，他表现为干咳。在调查过程中偶然发现右侧乳腺的 SFT，并将患者转介至比利时布鲁塞尔朱尔斯·博尔德研究所的乳腺诊所进行适当治疗。患者的表现、影像学和组织学样本均支持诊断，且他顺利接受了手术切除。在这里，我们报告了首例偶然发现的男性乳腺 SFT 病例，并讨论了其诊断和治疗挑战。
