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乳腺孤立性纤维瘤中的肿瘤内髓外造血。

Intratumoral extramedullary hematopoiesis in solitary fibrous tumor of the breast.

机构信息

Department of Pathology, Division of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.

Department of Pathology and Laboratory Medicine, Hartford Hospital, Hartford, Connecticut.

出版信息

Breast J. 2020 Apr;26(4):755-758. doi: 10.1111/tbj.13583. Epub 2019 Sep 4.

DOI:10.1111/tbj.13583
PMID:31486175
Abstract

Extramedullary hematopoiesis (EMH) is most often associated with underlying hematologic disorders, such as myeloproliferative neoplasms and thalassemia. EMH in the setting of solitary fibrous tumor (SFT) is exceedingly rare, with only 3 cases reported to date in the English literature. Herein, we describe our experience with a unique case of SFT arising in the breast with intratumoral foci of EMH in a 57-year-old woman who presented with an incidentally found right axillary mass on routine screening mammography. To the best of our knowledge, this is the first reported case of mammary SFT with concurrent intratumoral EMH.

摘要

骨髓外造血(EMH)通常与潜在的血液系统疾病相关,如骨髓增殖性肿瘤和地中海贫血。在孤立性纤维瘤(SFT)的情况下,EMH 非常罕见,迄今为止在英文文献中仅报道了 3 例。在此,我们描述了一位 57 岁女性的独特病例,她在右侧腋窝常规筛查乳房 X 线摄影时偶然发现一个肿块,该患者在乳房中发生 SFT 并伴有肿瘤内 EMH。据我们所知,这是首例报道的乳腺 SFT 伴肿瘤内 EMH 的病例。

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