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猴痘与药物重新利用:七种对抗该病毒性疾病的潜在抗病毒药物

Monkeypox and drug repurposing: seven potential antivirals to combat the viral disease.

作者信息

Varghese Ryan, Patel Pal, Kumar Dileep, Sharma Rohit

机构信息

Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune Maharashtra, India.

Department of Clinical Pharmacology, Advanced Centre for Treatment, Research, and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, India.

出版信息

Rev Environ Health. 2023 Feb 22;39(4):871-874. doi: 10.1515/reveh-2023-0001. Print 2024 Dec 17.

Abstract

The growing concern about the monkeypox (Mpox) virus infection has garnered a lot of public attention. However, the treatment options available to combat the same is limited to tecovirimat. Additionally, in a possible incidence of resistance, hypersensitivity, or adverse drug reaction, it is imperative to devise and reinforce the second-line therapy. Thus, in this editorial, the authors suggest seven antiviral drugs that could potentially be repurposed to combat the viral illness.

摘要

对猴痘病毒感染日益增长的担忧已引起公众广泛关注。然而,对抗该病毒的可用治疗选择仅限于特考韦瑞玛。此外,在可能出现耐药性、超敏反应或药物不良反应的情况下,制定并加强二线治疗至关重要。因此,在这篇社论中,作者建议了七种可能重新用于对抗这种病毒性疾病的抗病毒药物。

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