School of Health and Behavioural Sciences, Australian Catholic University, Brisbane, Australia.
School of Health and Behaviour Sciences, University of the Sunshine Coast, Maroochydore, Australia.
Phys Ther Sport. 2023 May;61:1-10. doi: 10.1016/j.ptsp.2023.02.003. Epub 2023 Feb 13.
There is conflicting evidence regarding whether regular running is associated with knee osteoarthritis prevalence. Previous evidence reports lower knee osteoarthritis prevalence in recreational runners compared with professionals (with a higher training volume) and controls (who have a lower training volume). The aim of this systematic review and meta-analysis was to determine if weekly running volume is associated with knee osteoarthritis prevalence. Four databases (PubMed, Web of Science, Scopus and SPORTDiscus) were searched from earliest record to November 2021. Included studies must i) recruit participants who ran regularly and recorded weekly running volume; ii) include a control group (running <8 km per week); iii) record knee osteoarthritis prevalence (either by radiological imaging or self-reported diagnosis from a doctor or physiotherapist). Study bias was assessed using the Newcastle-Ottawa Scale (NOS). Pooled effects were estimated using a random effects model. Odds ratios with 95% prediction and confidence intervals are reported. Nine observational case control studies with a total of 12,273 participants (1272 runners) were included in the meta-analysis. Most of the included studies were rated as having a very high (n = 2) or high (n = 3) risk of bias on the Newcastle Ottawa Scale. There was no difference in knee osteoarthritis prevalence between runners and controls (OR = 0.97, 95% CI = 0.56 to 1.68). Runners undertaking 8-32.1 km (OR = 1.17, 95% CI = 0.77 to 1.80), 32.2-48 km (OR = 1.04, 95% CI = 0.48 to 2.31) or > 48 km per week (OR = 0.62, 95% CI = 0.35 to 1.10) did not exhibit higher knee osteoarthritis prevalence compared with controls. It is unclear whether running volume is associated with increased knee osteoarthritis prevalence, future large-scale, high quality prospective studies are required.
关于经常跑步是否与膝关节骨关节炎的患病率有关，目前证据相互矛盾。先前的证据表明，与专业运动员（训练量较高）和对照组（训练量较低）相比，休闲跑步者的膝关节骨关节炎患病率较低。本系统评价和荟萃分析的目的是确定每周跑步量是否与膝关节骨关节炎的患病率有关。从最早的记录到 2021 年 11 月，我们在四个数据库（PubMed、Web of Science、Scopus 和 SPORTDiscus）中进行了搜索。纳入的研究必须：i）招募经常跑步并记录每周跑步量的参与者；ii）包括对照组（每周跑步量<8 公里）；iii）记录膝关节骨关节炎的患病率（通过放射影像学或医生或物理治疗师的自我报告诊断）。使用纽卡斯尔-渥太华量表（NOS）评估研究偏倚。使用随机效应模型估计汇总效应。报告了 95%预测区间和置信区间的比值比。纳入的 9 项观察性病例对照研究共有 12273 名参与者（1272 名跑步者）纳入荟萃分析。大多数纳入的研究在纽卡斯尔渥太华量表上的偏倚风险被评为很高（n=2）或高（n=3）。跑步者与对照组之间的膝关节骨关节炎患病率没有差异（OR=0.97，95%CI=0.56 至 1.68）。每周跑步 8-32.1 公里（OR=1.17，95%CI=0.77 至 1.80）、32.2-48 公里（OR=1.04，95%CI=0.48 至 2.31）或每周跑步超过 48 公里（OR=0.62，95%CI=0.35 至 1.10）的跑步者膝关节骨关节炎患病率并未高于对照组。目前尚不清楚跑步量是否与膝关节骨关节炎患病率增加有关，需要进行大规模、高质量的前瞻性研究。
