Bai Jiaqi, Wang Zixin, Zhong Chengjian, Hou Shaojie, Lian Jiaqi, Si Qiankang, Gao Feng, Zhang Feng
The School of Biomedical Engineering, Guangzhou Medical University, Xinzao Town, Panyu District, Guangzhou, 511436, China.
Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Biochem Biophys Res Commun. 2023 Apr 16;652:31-34. doi: 10.1016/j.bbrc.2023.02.025. Epub 2023 Feb 12.
Vibrational strong coupling (VSC) has been reported as a polariton-based method for modulating the rate of biochemical reactions. Herein, we studied how VSC modulates the sucrose hydrolysis. By monitoring the refractive index-induced shift of Fabry-Pérot microcavity, in which the catalytic efficiency of sucrose hydrolysis can be increased at least two times, as VSC was tuned to resonate with the stretching vibration of O-H bonds. This research provides new evidence for applying VSC in life sciences, which holds great promise to improving enzymatic industries.
振动强耦合（VSC）已被报道为一种基于极化激元的调节生化反应速率的方法。在此，我们研究了VSC如何调节蔗糖水解。通过监测法布里-珀罗微腔的折射率诱导位移，当VSC被调谐到与O-H键的拉伸振动共振时，蔗糖水解的催化效率可提高至少两倍。这项研究为VSC在生命科学中的应用提供了新证据，有望改善酶促工业。
