Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States.
Neuropediatrics. 2024 Feb;55(1):67-70. doi: 10.1055/a-2039-4425. Epub 2023 Feb 21.
Limited data are available regarding the impact of the coronavirus disease 2019 (COVID-19) pandemic on adolescents with Tourette syndrome (TS). We sought to compare sex differences in tic severity experienced by adolescents before and during the COVID-19 pandemic. We extracted from the electronic health record and retrospectively reviewed Yale Global Tic Severity Scores (YGTSS) from adolescents (ages 13 through 17) with TS presenting to our clinic before (36 months) and during (24 months) the pandemic. A total of 373 unique adolescent patient encounters (prepandemic: 199; pandemic: 173) were identified. Compared with prepandemic, girls accounted for a significantly greater proportion of visits during the pandemic ( < 0.001). Prepandemic, tic severity did not differ between girls and boys. During the pandemic, compared with girls, boys had less clinically severe tics ( = 0.003). During the pandemic, older girls, but not boys, had less clinically severe tics ( =- 0.32, = 0.003). These findings provide evidence that, regarding tic severity assessed with YGTSS, the experiences of adolescent girls and boys with TS have differed during the pandemic.
关于 2019 年冠状病毒病（COVID-19）大流行对患有图雷特综合征（TS）的青少年的影响，相关数据有限。我们试图比较 COVID-19 大流行前后青少年 tic 严重程度的性别差异。我们从电子健康记录中提取，并回顾性地审查了在我们诊所就诊的患有 TS 的青少年（年龄在 13 至 17 岁）的耶鲁全球 tic 严重程度评分（YGTSS），这些青少年在大流行之前（36 个月）和期间（24 个月）就诊。共确定了 373 个独特的青少年患者就诊（大流行前：199；大流行期间：173）。与大流行前相比，女孩在大流行期间就诊的比例明显更高（ < 0.001）。大流行前，女孩和男孩的 tic 严重程度没有差异。在大流行期间，与女孩相比，男孩 tic 严重程度较轻（ = 0.003）。在大流行期间，年龄较大的女孩而不是男孩 tic 严重程度较轻（ =- 0.32， = 0.003）。这些发现提供了证据表明，在 YGTSS 评估的 tic 严重程度方面，患有 TS 的青少年女孩和男孩的经历在大流行期间有所不同。
