Ophthalmology, Tennent Institute of Ophthalmology, Glasgow, UK
Ophthalmology, Tennent Institute of Ophthalmology, Glasgow, UK.
BMJ Case Rep. 2023 Feb 21;16(2):e253014. doi: 10.1136/bcr-2022-253014.
The clinical course of adenoviral pseudomembranous conjunctivitis is mostly self-limiting and requires only supportive management measures; however, a minority of patients may develop severe inflammation in response to the virus, which can present as subepithelial infiltrates and pseudomembranes. In its most severe form, symblepharon can result from the inflammatory response resulting in longer-term clinical sequelae. The optimal management of adenoviral pseudomembranous conjunctivitis is poorly defined and while debridement is commonly recommended, there is limited evidence base to support this practice. In this paper, we present two cases of PCR-proven adenoviral pseudomembranous conjunctivitis managed conservatively with topical lubricants and corticosteroids rather than debridement to good effect.
腺病毒伪膜性结膜炎的临床病程大多是自限性的，只需支持性的治疗措施即可；然而，少数患者可能会对病毒产生严重的炎症反应，表现为上皮下浸润和伪膜。在最严重的情况下，炎症反应可能导致融合性眼睑粘连，从而导致长期的临床后遗症。腺病毒伪膜性结膜炎的最佳治疗方法尚未明确，虽然常规推荐清除伪膜，但支持这种治疗方法的证据有限。本文介绍了两例经 PCR 证实的腺病毒伪膜性结膜炎患者，采用局部润滑剂和皮质类固醇保守治疗，而不是清除伪膜，取得了良好的效果。
