Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14850, USA.
Current address: Department of Chemistry, Princeton University, Princeton, NJ, 08544, USA.
Angew Chem Int Ed Engl. 2023 Apr 17;62(17):e202218252. doi: 10.1002/anie.202218252. Epub 2023 Mar 16.
Metal-organic frameworks (MOFs) are porous, crystalline materials constructed from organic linkers and inorganic nodes with myriad potential applications in chemical separations, catalysis, and drug delivery. A major barrier to the application of MOFs is their poor scalability, as most frameworks are prepared under highly dilute solvothermal conditions using toxic organic solvents. Herein, we demonstrate that combining a range of linkers with low-melting metal halide (hydrate) salts leads directly to high-quality MOFs without added solvent. Frameworks prepared under these ionothermal conditions possess porosities comparable to those prepared under traditional solvothermal conditions. In addition, we report the ionothermal syntheses of two frameworks that cannot be prepared directly under solvothermal conditions. Overall, the user-friendly method reported herein should be broadly applicable to the discovery and synthesis of stable metal-organic materials.
金属-有机骨架（MOFs）是由有机配体和无机节点构建的多孔晶体材料，在化学分离、催化和药物输送等领域具有广泛的应用前景。MOFs 的应用主要受到其较差的可扩展性的限制，因为大多数框架都是在高度稀释的溶剂热条件下使用有毒有机溶剂制备的。在此，我们证明了将一系列配体与低熔点金属卤化物（水合物）盐结合，可以直接得到高质量的 MOFs，而无需添加溶剂。在这些离子热条件下制备的框架具有与传统溶剂热条件下制备的框架相当的孔隙率。此外，我们还报告了两种不能直接在溶剂热条件下制备的框架的离子热合成。总的来说，本文报道的这种使用方便的方法应该广泛适用于稳定的金属-有机材料的发现和合成。
