Ayyash H, Hadjigeorgiou E, Sofatzis J, Chatziioannou A, Nicolopoulos D, Sideris E
Second Department of Pediatrics, University of Athens Medical School, Leto, Maternity Hospital, Greece.
J Pediatr. 1987 Dec;111(6 Pt 1):882-7. doi: 10.1016/s0022-3476(87)80211-1.
The efficacy of fluorescent green light phototherapy was compared with that of blue light phototherapy in the treatment of full-term infants with hemolytic disease and jaundice caused by ABO incompatibility. The efficacy of the treatment was expressed as actual (milligrams per hour) and quantum (milligrams per hour per square centimeter per megawatt) efficiency, taking into account the differential emission of energy from the green versus the blue fluorescent tubes. No statistically significant difference in the rate of serum bilirubin photodegradation was found between the two groups after treatment for 84.6 +/- 14.1 hours versus 81.5 +/- 14.2 hours with the green and the blue phototherapy, respectively. These results, coupled with the known effects of the blue light on the genetic apparatus of mammalian cells, support the application of the green light phototherapy for the treatment of neonatal hyperbilirubinemia caused by ABO incompatibility.
将荧光绿光光疗与蓝光光疗治疗ABO血型不合所致溶血性疾病及黄疸足月儿的疗效进行了比较。治疗效果以实际(每小时毫克数)和量子(每平方厘米每兆瓦每小时毫克数)效率表示,同时考虑到绿色与蓝色荧光灯管能量发射的差异。分别采用绿光和蓝光光疗治疗84.6±14.1小时和81.5±14.2小时后,两组血清胆红素光降解率无统计学显著差异。这些结果,再加上蓝光对哺乳动物细胞遗传机制的已知影响,支持将绿光光疗应用于治疗ABO血型不合所致新生儿高胆红素血症。