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扩大椎板切除术联合侧块螺钉固定治疗脊髓型颈椎病和神经根型颈椎病以缓解神经根症状及矫正后凸畸形的疗效评估

Evaluation of enlarged laminectomy with lateral mass screw fixation in relieving nerve root symptoms and correcting kyphosis for cervical myelopathy and radiculopathy.

作者信息

Fang Zhao, Li Yuqiao, Huang Zongyu, Luo Gan, Yang Houzhi, Cheng Haiyang, Xu Tiantong

机构信息

Department of Spine Surgery, Tianjin Union Medical Center, Tianjin, China.

Graduate School, Tianjin Medical University, Tianjin, China.

出版信息

Front Surg. 2023 Feb 2;10:1103804. doi: 10.3389/fsurg.2023.1103804. eCollection 2023.

Abstract

PURPOSE

This study aimed to compare the surgical efficacy of enlarged laminectomy with lateral mass screw fixation (EL-LMSF) and anterior cervical decompression and fusion (ACDF) for multilevel cervical myelopathy and radiculopathy (CMR) related to kyphosis.

METHODS

75 patients were retrospectively reviewed and divided into ACDF and EL-LMSF group. Clinical results including operative time, blood loss, and postoperative complications were compared. The JOA scoring system was used to evaluate spinal cord function and the VAS score evaluate nerve root pain severity. Cervical alignment a C2-C7 was measured with Cobb method and compared to confirm the reconstruction effect.

RESULTS

Data on 75 patients (M/F: 41:34; EL-LMSF/ACDF:42/33) with the mean age of 57.5 years (range 43-72 year old) were reviewed retrospectively. Discectomy and/or sub-toal corpectomy in ACDF group was performed with a mean of 3.24 levels (range, 3-4). Enlarged laminectomy in EL-LMSF group was performed with a mean of 3.89 enlarged levels (range, 3-5). The procedure of ACDF group showed a shorter operation time (103 ± 22 min vs. 125 ± 37 min,  = 0.000) and less blood loss (78 ± 15 ml vs. 226 ± 31 ml,  = 0.000) compared than that of the EL-LMSF group. Patients treated with EL-LMSF indicated lower VAS for upper extremity (1.3 ± 1.7 vs. 3.3 ± 1.3,  = 0.003) and better curvature corrected (10.7 ± 4.2° vs. 8.5 ± 3.5°,  = 0.013). The difference were of statistical significance. No statistical difference was found after surgery in the JOA score (14.1 ± 1.7 vs. 13.5 ± 2.1,  = 0.222). During the follow-up period, 15.2% of patients in the ACDF group had complications including 2 cases with transient dysphagia, 1 case with C5 palsy, 1 case with axial pain, and 1 case with screw pullout 3 month after surgery. However, only 9.5% of cases in the EL-LMSF group experienced complications, including 3 cases of axial pain and 1 case of epidural hematoma.

CONCLUSION

The EL-LMSF procedure requires a longer operation time and more blood loss because of the incision of the stenosed foramen. However, the procedure has obvious advantages in relieving nerve root symptoms and correcting cervical curvature with fewer postoperative complications.

摘要

目的

本研究旨在比较扩大椎板切除术联合侧块螺钉固定(EL-LMSF)与颈椎前路减压融合术(ACDF)治疗与后凸相关的多节段颈椎脊髓病和神经根病(CMR)的手术疗效。

方法

回顾性分析75例患者,并将其分为ACDF组和EL-LMSF组。比较两组的临床结果,包括手术时间、失血量和术后并发症。采用JOA评分系统评估脊髓功能,采用VAS评分评估神经根疼痛严重程度。用Cobb法测量C2-C7节段的颈椎排列情况,并进行比较以确认重建效果。

结果

回顾性分析了75例患者的数据(男/女:41/34;EL-LMSF/ACDF:42/33),平均年龄57.5岁(范围43-72岁)。ACDF组平均进行3.24节段(范围3-4节段)的椎间盘切除术和/或次全椎体切除术。EL-LMSF组平均进行3.89个扩大节段(范围3-5节段)的扩大椎板切除术。ACDF组手术时间较短(103±22分钟 vs. 125±37分钟,P = 0.000),失血量较少(78±15毫升 vs. 226±31毫升,P = 0.000)。接受EL-LMSF治疗的患者上肢VAS评分较低(1.3±1.7 vs. 3.3±1.3,P = 0.003),颈椎曲度矫正效果更好(10.7±4.2° vs. 8.5±3.5°,P = 0.013)。差异具有统计学意义。术后JOA评分无统计学差异(14.1±1.7 vs. 13.5±2.1,P = 0.222)。随访期间,ACDF组15.2%的患者出现并发症,包括2例短暂性吞咽困难、1例C5麻痹、1例轴性疼痛和1例术后3个月螺钉拔出。然而,EL-LMSF组仅9.5%的病例出现并发症,包括3例轴性疼痛和1例硬膜外血肿。

结论

由于切开狭窄的椎间孔,EL-LMSF手术需要更长的手术时间和更多的失血量。然而,该手术在缓解神经根症状和矫正颈椎曲度方面具有明显优势,术后并发症较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b61/9934924/f01eccfdbbe5/fsurg-10-1103804-g001.jpg

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