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一项关于新冠后突发性感音神经性听力损失及其恢复的前瞻性研究。

A Prospective Study on Post Covid Sudden Onset Sensory Neural Hearing Loss and Its Recovery.

作者信息

Kandakure Vinod T, Kunjumon Riya, Dube Yashaswi, More Madhuri S, Garje Shilpa

机构信息

Department of ENT, Dr Shankarraochavan Government Medical College, Nanded, India.

Latur, Maharashtra India Department of ENT, Vilasrao Deshmukh Government Medical College.

出版信息

Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):451-457. doi: 10.1007/s12070-023-03529-3. Epub 2023 Feb 14.

DOI:10.1007/s12070-023-03529-3
PMID:36817015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9926405/
Abstract

Sudden sensorineural hearing loss (SSNHL) is a known complication of a number of viral infections, but there is little literature to date on its association to Corona virus disease 2019(COVID-19).This study aimed to investigate the incidence and recovery from SSNHL in post COVID-19 patients. A study was conducted in 6 months of duration at our tertiary care COVID dedicated hospital. Total 280 patients with age group of 12-70 years, laboratory confirmed COVID 19 positive patients having mild to moderate COVID symptoms were included. Patients were examined clinically along with all safety measures to analyze incidence and their recoveries from SSNHL by clinical examination and using Pure Tone Audiometry (PTA). Out of 280 patients the incidence of only SSNHL is 1.07% (3 patients) and SSNHL with tinnitus is 2.14%(6 patients).Total recovery(TR) regained in 2 patients of SSNHL, Partial recovery(PR) in 4 patients, Slight improvement(SI) in 1 patient and no recovery(NR) in 2 patients. The incidence of SSNHL in time of COVID 19 pandemic appears to be higher (3.2%) than before the pandemic (0.005%-0.16%). Incidence among younger age group and patients with no comorbidities has been also increased. In diagnosed case of SSNHL, early treatment with short term course of oral steroids and neuromodulator drugs are the mainstay treatment. Awareness of such non-specific presentation of COVID 19 patients is crucial and shared decision making with the patient and providing health care personnel is necessary for decreasing the hearing loss associated morbidity.

摘要

突发性感音神经性听力损失(SSNHL)是多种病毒感染的已知并发症,但迄今为止关于其与2019冠状病毒病(COVID-19)关联的文献很少。本研究旨在调查COVID-19康复患者中SSNHL的发病率及康复情况。在我们的三级护理COVID专科医院进行了为期6个月的研究。纳入了年龄在12至70岁之间、实验室确诊为COVID-19阳性且有轻度至中度COVID症状的280名患者。对患者进行临床检查并采取所有安全措施,通过临床检查和使用纯音听力计(PTA)分析SSNHL的发病率及其康复情况。在280名患者中,仅SSNHL的发病率为1.07%(3例患者),伴有耳鸣的SSNHL发病率为2.14%(6例患者)。2例SSNHL患者实现了完全康复(TR),4例部分康复(PR),1例稍有改善(SI),2例未康复(NR)。COVID-19大流行期间SSNHL的发病率似乎高于大流行前(0.005%-0.16%),为3.2%。年轻年龄组和无合并症患者中的发病率也有所增加。对于确诊的SSNHL病例,短期口服类固醇和神经调节剂药物的早期治疗是主要治疗方法。认识到COVID-19患者的这种非特异性表现至关重要,与患者共同决策并为医护人员提供必要信息对于降低与听力损失相关的发病率很有必要。

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