Cheng Yaonan, Chen Qin, Huang Ru, Lao Chunbo, Fu Wenbin
Department of Acupuncture, Gaozhou Hospital of Traditional Chinese Medicine, Gaozhou, Guangdong, China.
Department of Internal Medicine, Gaozhou Hospital of Traditional Chinese Medicine, Gaozhou, Guangdong, China.
Arch Med Sci. 2023 Jan 13;19(1):258-263. doi: 10.5114/aoms/155982. eCollection 2023.
This study aimed to investigate the potential role of moxibustion (MOX) in the treatment of lung infection in patients bed-ridden due to osteoporotic fracture of the spine.
96 senile patients with pulmonary infection who were bed-ridden due to osteoporotic fracture of the spine were grouped into a MOX (-) group and a MOX (+) group. An animal model was established as a SHAM group, a PRIMED group, a MOX 15' group and a MOX 30' group.
For the patients' study, we found that the survival rate was higher for patients who received MOX. Moreover, tumor necrosis factor-α, interleukin (IL) 1β, IL-6 and IL-18 were down-regulated while IL-10 was up-regulated by MOX. MOX time-dependently increased the survival while reducing the bacteria left in infected mice.
Moxibustion significantly alleviated the inflammatory responses, thus leading to a better survival rate of patients bed-ridden due to osteoporotic fracture of the spine.
本研究旨在探讨艾灸在治疗因脊柱骨质疏松性骨折而卧床的患者肺部感染中的潜在作用。
96例因脊柱骨质疏松性骨折而卧床的老年肺部感染患者被分为艾灸（-）组和艾灸（+）组。建立动物模型，分为假手术组、预处理组、艾灸15分钟组和艾灸30分钟组。
在患者研究中，我们发现接受艾灸的患者生存率更高。此外，艾灸可下调肿瘤坏死因子-α、白细胞介素（IL）-1β、IL-6和IL-18，而上调IL-10。艾灸能随时间增加生存率，同时减少感染小鼠体内残留的细菌。
艾灸显著减轻炎症反应，从而使因脊柱骨质疏松性骨折而卧床的患者生存率更高。
