Zeinalpour Adel, Berjouei Hossein Zolfaghari, Gholizadeh Barmak
Department of General Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Clinical Research Development Center, Shahid Modarres Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Maedica (Bucur). 2022 Dec;17(4):840-845. doi: 10.26574/maedica.2022.17.4.840.
The aim of this study was to compare the perioperative outcomes and complications between pancreaticoduodenectomy (PD) candidates with and without jejunostomy tube (J-tube) feeding. This retrospective cohort study was performed on 48 patient candidates for PD, with or without J-tube placement during surgery, in Shahid Modarres Hospital, Tehran, Iran, between 2013 and 2021. Two groups were matched for age, gender, history of heart, endocrine, hypertension and kidney diseases, and drug use. A 12 French jejunal feeding tube was placed at 20-30 cm distal to gastrojejunostomy anastomosis. Outcomes, including biliary leak, postoperative pancreatic fistula (POPF), delayed gastric emptying (DGE), surgical site infection (SSI), intra-abdominal infection, duration of nasogastric tube (NGT) stay, postoperative (PO) tolerance length, need for total parenteral nutrition (TPN), hospitalization length, and mortality rate, were assessed. There were eight cases with leak (37.5% J-tube group, of which six (75%) were pancreatic type and two (25%) biliary type. There were 11 (22.9%) patients with DGE (54.5% in J-tube group). There was no significant inter-group difference in SSI (P=0.340), intra-abdominal infection managed non-invasively (P=0.369), intra-abdominal abscess managed by percutaneous drainage (P=0.158), patients requiring TPN (P=0.447), NGT placement duration (P=0.088), PO tolerance time (P=0.327), hospital stay (P=0.760) and mortality rate (P=0.851). J-tube placement after PD for pancreatic cancer may be associated with increased postoperative complications. The conclusion of the present study is that there is no difference between performing and not performing the J-tube placement method in terms of complications and consequences.
本研究的目的是比较有和没有空肠造口管(J管)喂养的胰十二指肠切除术(PD)候选患者的围手术期结局和并发症。这项回顾性队列研究于2013年至2021年期间在伊朗德黑兰的沙希德·莫达雷斯医院对48例PD候选患者进行,这些患者在手术期间有或没有放置J管。两组在年龄、性别、心脏、内分泌、高血压和肾脏疾病史以及药物使用方面进行了匹配。在胃空肠吻合口远端20 - 30 cm处放置一根12法式空肠喂养管。评估了包括胆漏、术后胰瘘(POPF)、胃排空延迟(DGE)、手术部位感染(SSI)、腹腔内感染、鼻胃管(NGT)留置时间、术后(PO)耐受时长、全胃肠外营养(TPN)需求、住院时长和死亡率等结局。有8例发生渗漏(J管组占37.5%,其中6例(75%)为胰瘘型,2例(25%)为胆瘘型)。有11例(22.9%)发生DGE患者(J管组占54.5%)。两组在SSI(P = 0.340)、非侵入性处理的腹腔内感染(P = 0.369)、经皮引流处理的腹腔内脓肿(P = 0.158)、需要TPN的患者(P = 0.447)、NGT放置时长(P = 0.088)、PO耐受时间(P = 0.327)、住院时间(P = 0.760)和死亡率(P = 0.851)方面无显著组间差异。胰腺癌PD术后放置J管可能与术后并发症增加有关。本研究的结论是,在并发症和后果方面,J管放置方法实施与否并无差异。