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Commentary: Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy.评论：经证实的非综合征性主动脉病变患者的转化生长因子血清浓度
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A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor β-1 to Soluble Endoglin Ratio.可能用于二叶式主动脉瓣病变的早期生物标志物：循环转化生长因子 β-1 与可溶性内皮糖蛋白比值。
Circ Res. 2017 May 26;120(11):1800-1811. doi: 10.1161/CIRCRESAHA.117.310833. Epub 2017 Apr 18.
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Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy.经证实患有非综合征性主动脉病变患者的转化生长因子血清浓度。
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Increased blood levels of transforming growth factor β in patients with aortic dilatation.主动脉扩张患者血液中转化生长因子β水平升高。
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Epigenetic regulation of TGF-β1 signalling in dilative aortopathy of the thoracic ascending aorta.胸主动脉扩张性病变中转化生长因子-β1信号通路的表观遗传调控
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Hypothesis-free secretome analysis of thoracic aortic aneurysm reinforces the central role of TGF-β cascade in patients with bicuspid aortic valve.胸主动脉瘤的无假设分泌蛋白组分析强化了转化生长因子-β级联反应在二叶式主动脉瓣患者中的核心作用。
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The aortic stenosis complex: aortic valve, atherosclerosis, aortopathy.主动脉瓣狭窄综合征：主动脉瓣、动脉粥样硬化、主动脉病变。
J Cardiol. 2015 May;65(5):377-82. doi: 10.1016/j.jjcc.2014.12.021. Epub 2015 Apr 15.
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Bicuspid aortic valve: phosphorylation of c-Kit and downstream targets are prognostic for future aortopathy.二叶式主动脉瓣：c-Kit 及其下游靶点的磷酸化对未来主动脉病变具有预后意义。
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Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling.马凡综合征小鼠模型中的主动脉病变并非由转化生长因子β信号改变介导。
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The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary.美国胸外科学会关于二叶式主动脉瓣相关主动脉瓣病变的共识指南：执行摘要。
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Emerging imaging and circulating biomarkers in relation to underlying mechanisms in Bicuspid Aortic Valve aortopathy.与二叶式主动脉瓣主动脉病变潜在机制相关的新兴影像学和循环生物标志物。
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本文引用的文献
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Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy.经证实患有非综合征性主动脉病变患者的转化生长因子血清浓度。
Front Cardiovasc Med. 2022 Sep 6;9:980103. doi: 10.3389/fcvm.2022.980103. eCollection 2022.
2
Normal and abnormal development of the aortic valve and ascending aortic wall: a comprehensive overview of the embryology and pathology of the bicuspid aortic valve.主动脉瓣和升主动脉壁的正常与异常发育：二叶式主动脉瓣胚胎学与病理学的全面概述
Ann Cardiothorac Surg. 2022 Jul;11(4):380-388. doi: 10.21037/acs-2021-bav-14.
3
Comparative evaluation of coronary disease burden: bicuspid valve disease is not atheroprotective.冠状动脉疾病负担的比较评估：二叶式主动脉瓣病变并非动脉粥样硬化的保护因素。
Open Heart. 2021 Sep;8(2). doi: 10.1136/openhrt-2021-001772.
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Extent of Coronary Artery Disease in Patients With Stenotic Bicuspid Versus Tricuspid Aortic Valves.狭窄性二叶瓣主动脉瓣与三叶瓣主动脉瓣患者的冠状动脉疾病严重程度。
J Am Heart Assoc. 2021 Jun 15;10(12):e020080. doi: 10.1161/JAHA.120.020080. Epub 2021 Jun 2.
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A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation.A型主动脉夹层的系统组织病理学评估提示其病因是统一的多因素致病。
J Cardiovasc Dev Dis. 2021 Jan 27;8(2):12. doi: 10.3390/jcdd8020012.
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Comparison of microstructural alterations in the proximal aorta between aortic stenosis and regurgitation.比较主动脉瓣狭窄与反流患者升主动脉微观结构改变。
J Thorac Cardiovasc Surg. 2021 Dec;162(6):1684-1695. doi: 10.1016/j.jtcvs.2020.03.002. Epub 2020 Mar 12.
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The Development of the Ascending Aortic Wall in Tricuspid and Bicuspid Aortic Valve: A Process from Maturation to Degeneration.三尖瓣和二尖瓣主动脉瓣升主动脉壁的发育：从成熟到退变的过程
J Clin Med. 2020 Mar 26;9(4):908. doi: 10.3390/jcm9040908.
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Pathogenesis of aortic wall complications in Marfan syndrome.马凡综合征主动脉壁并发症的发病机制。
Cardiovasc Pathol. 2018 Mar-Apr;33:62-69. doi: 10.1016/j.carpath.2018.01.005. Epub 2018 Feb 2.
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A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor β-1 to Soluble Endoglin Ratio.可能用于二叶式主动脉瓣病变的早期生物标志物：循环转化生长因子 β-1 与可溶性内皮糖蛋白比值。
Circ Res. 2017 May 26;120(11):1800-1811. doi: 10.1161/CIRCRESAHA.117.310833. Epub 2017 Apr 18.
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Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria.心血管病理学会和欧洲心血管病理学会关于主动脉手术病理学的共识声明：II. 非炎性退行性疾病——命名与诊断标准
Cardiovasc Pathol. 2016 May-Jun;25(3):247-257. doi: 10.1016/j.carpath.2016.03.002. Epub 2016 Mar 12.
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