Vanani Naisarg B, Stevanovic Stephen G, Stevanovic Nebojsa
College of Medicine, Medical College of Wisconsin, Milwaukee, USA.
Family Medicine, Ascension St. Francis Hospital, Milwaukee, USA.
Cureus. 2023 Jan 15;15(1):e33809. doi: 10.7759/cureus.33809. eCollection 2023 Jan.
Kratom () is a tropical evergreen plant native to Southeast Asia, where it has been used historically for its various psychoactive and analgesic properties. In recent years, the popularity of kratom has surged in the United States as a supplement for treating opioid withdrawal/addiction, anxiety, depression, and chronic pain, among others. However, much of Kratom processing and sales remain largely unregulated, with little clinical research to demonstrate the effects of kratom on physiologic processes such as potential drug interactions. Here, we present a case of Kratom interaction with Amitriptyline in a patient recovering from Opioid Use Disorder.
kratom（）是一种原产于东南亚的热带常绿植物，在历史上因其具有多种精神活性和止痛特性而被使用。近年来，kratom在美国作为一种治疗阿片类药物戒断/成瘾、焦虑、抑郁和慢性疼痛等疾病的补充剂，其受欢迎程度激增。然而，kratom的大部分加工和销售在很大程度上仍未得到监管，几乎没有临床研究来证明kratom对诸如潜在药物相互作用等生理过程的影响。在此，我们报告一例在从阿片类药物使用障碍中康复的患者中kratom与阿米替林相互作用的病例。
