Division of Environmental Hazards and Health Effects, National Center for Environmental Health, CDC.
MMWR Morb Mortal Wkly Rep. 2016 Jul 29;65(29):748-9. doi: 10.15585/mmwr.mm6529a4.
Kratom (Mitragyna speciosa) is a plant consumed throughout the world for its stimulant effects and as an opioid substitute (1). It is typically brewed into a tea, chewed, smoked, or ingested in capsules (2). It is also known as Thang, Kakuam, Thom, Ketum, and Biak (3). The Drug Enforcement Administration includes kratom on its Drugs of Concern list (substances that are not currently regulated by the Controlled Substances Act, but that pose risks to persons who abuse them), and the National Institute of Drug Abuse has identified kratom as an emerging drug of abuse (3,4). Published case reports have associated kratom exposure with psychosis, seizures, and deaths (5,6). Because deaths have been attributed to kratom in the United States (7), some jurisdictions have passed or are considering legislation to make kratom use a felony (8). CDC characterized kratom exposures that were reported to poison centers and uploaded to the National Poison Data System (NPDS) during January 2010-December 2015. The NPDS is a national database of information logged by the country's regional poison centers serving all 50 United States, the District of Columbia, and Puerto Rico and is maintained by the American Association of Poison Control Centers. NPDS case records are the result of call reports made by the public and health care providers.
Kratom(Mitragyna speciosa)是一种在世界各地被消费的植物,因其具有刺激作用和作为阿片类药物替代品而受到青睐(1)。它通常被泡成茶,咀嚼,吸烟或制成胶囊服用(2)。它也被称为 Thang,Kakuam,Thom,Ketum 和 Biak(3)。缉毒署将 kratom 列入其关注药物清单(目前不受《管制药物法》管制,但对滥用者构成风险的物质),国家药物滥用研究所已将 kratom 确定为新兴的滥用药物(3,4)。已发表的病例报告将 kratom 暴露与精神病,癫痫发作和死亡联系起来(5,6)。由于在美国已将 kratom 死亡归因于 kratom(7),因此一些司法管辖区已经通过或正在考虑立法将 kratom 使用定为重罪(8)。CDC 对 2010 年 1 月至 2015 年 12 月期间向国家毒物数据系统(NPDS)报告并上传至该系统的毒物中心报告的 kratom 暴露情况进行了描述。NPDS 是一个国家数据库,由美国各地的地区毒物中心提供信息,这些中心为美国 50 个州、哥伦比亚特区和波多黎各提供服务,由美国中毒控制中心协会维护。NPDS 病例记录是公众和医疗保健提供者拨打报告电话的结果。