Imam Syed K, Hassan Fatima M, Mohamed Hossam
Internal Medicine Department, Sultan Bin Abdulaziz Humanitarian City, Riyadh, SAU.
Nursing Department, Sultan Bin Abdulaziz Humanitarian City, Riyadh, SAU.
Cureus. 2023 Jan 16;15(1):e33847. doi: 10.7759/cureus.33847. eCollection 2023 Jan.
Latent autoimmune diabetes in adults (LADA) is a common but not well-studied entity and its features overlap between type 1 and type 2 diabetes mellitus (T1D, T2D). Although autoimmunity is a well-known factor associated with this diabetes subtype, environmental factors including excessive weight, physical inactivity, and smoking may also be associated with it. It is commonly misdiagnosed as T2D and generally treated by oral anti-diabetes medications that cause a delay in commencing insulin therapy. There are few cases mentioned in the literature of LADA presenting first time as diabetic ketoacidosis (DKA). Here, we report a case of latent autoimmune diabetes in an adult male who presented with DKA.
成人隐匿性自身免疫性糖尿病(LADA)是一种常见但研究尚不充分的疾病实体,其特征在1型和2型糖尿病(T1D、T2D)之间存在重叠。虽然自身免疫是与这种糖尿病亚型相关的一个众所周知的因素,但包括体重过重、缺乏运动和吸烟在内的环境因素也可能与之相关。它常被误诊为T2D,通常采用口服抗糖尿病药物治疗,这会导致胰岛素治疗开始延迟。文献中很少有LADA首次表现为糖尿病酮症酸中毒(DKA)的病例报道。在此,我们报告一例成年男性隐匿性自身免疫性糖尿病患者,该患者以DKA就诊。