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心内膜炎:一种伴有侵袭性全身栓塞且需要进行瓣膜置换的罕见病因。

Endocarditis: A Rare Cause with Aggressive Systemic Embolisation and Need of Valve Replacement.

作者信息

Cochicho Ramalho Ana, Marques Santos Sofia, Abecasis Joao, Rodrigues Rui, Araújo Francisco, Cantante Helena

机构信息

Internal Medicine Department, Hospital Lusíadas, Lisboa, Portugal.

Cardiology Department, Hospital Lusíadas, Lisboa, Portugal.

出版信息

Eur J Case Rep Intern Med. 2023 Jan 9;10(1):003702. doi: 10.12890/2023_003702. eCollection 2023.

Abstract

UNLABELLED

Infective endocarditis (IE) is a well-described infectious disease, one with increased morbidity and mortality being the third or fourth most common life-threatening infection syndrome. is a non-motile, catalase negative, gram-positive coccus in a chain, which can be isolated from the oral cavity, intestinal, and genitourinary tracts. IE due to this agent is rare and associated with heart valve destruction, congestive heart failure, and high embolisation rates, these being the major mortality causes. We present a case of IE due to this agent, complicated with a stroke, and splenic and renal infarction, with the need for aortic valve replacement. This article highlights the gaps of knowledge left by the rarity of this disease, which range from its diagnosis to its treatment, and what we need to mitigate such gaps, supported with a case description of a successful treatment of this infection.

LEARNING POINTS

Infective endocarditis due to has usually an indolent course, but the embolisation potential is very high.The major causes of mortality with this species are congestive heart failure due to valve destruction and the presence of multiple emboli.Surgical intervention rates are high with , reaching 50% of cases.

摘要

未标注

感染性心内膜炎(IE)是一种已被充分描述的传染病,是发病率和死亡率增加的第三或第四种最常见的危及生命的感染综合征。[具体细菌名称未给出]是一种无动力、过氧化氢酶阴性、呈链状的革兰氏阳性球菌,可从口腔、肠道和泌尿生殖道分离出来。由该病原体引起的IE很罕见,与心脏瓣膜破坏、充血性心力衰竭和高栓塞率相关,这些是主要的死亡原因。我们报告一例由该病原体引起的IE病例,并发中风、脾梗死和肾梗死,需要进行主动脉瓣置换。本文强调了这种罕见疾病在从诊断到治疗方面所留下的知识空白,以及我们为弥合这些差距所需要做的事情,并辅以该感染成功治疗的病例描述。

学习要点

由[具体细菌名称未给出]引起的感染性心内膜炎通常病程缓慢,但栓塞风险非常高。该菌种导致死亡的主要原因是瓣膜破坏引起的充血性心力衰竭和存在多个栓子。[具体细菌名称未给出]的手术干预率很高,达到病例的50%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3efd/9930876/eaebf0d10d61/3702_Fig1.jpg

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