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使用神经网络预测新冠康复患者家庭氧疗的分类

Predicting the Classification of Home Oxygen Therapy for Post-COVID-19 Rehabilitation Patients Using a Neural Network.

作者信息

Nakamura Kensuke, Mazaki Lisa, Hayashi Yukiko, Tsuji Taro, Furusawa Hiroki

机构信息

Department of Rehabilitation, Amagasaki Medical Co-operative Hospital, Japan.

出版信息

Phys Ther Res. 2022;25(3):99-105. doi: 10.1298/ptr.E10181. Epub 2022 Dec 22.

DOI:10.1298/ptr.E10181
PMID:36819912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9910350/
Abstract

OBJECTIVE

We evaluated the accuracy of a neural network to classify and predict the possibility of home oxygen therapy at the time of discharge from hospital based on patient information post-coronavirus disease (COVID-19) at admission.

METHODS

Patients who survived acute treatment with COVID-19 and were admitted to the Amagasaki Medical Co-operative Hospital during August 2020-December 2021 were included. However, only rehabilitation patients (n = 88) who were discharged after a rehabilitation period of at least 2 weeks and not via home or institution were included. The neural network model implemented in R for Windows (4.1.2) was trained using data on patient age, gender, and number of days between a positive polymerase chain reaction test and hospitalization, length of hospital stay, oxygen flow rate required at hospitalization, and ability to perform activities of daily living. The number of training trials was 100. We used the area under the curve (AUC), accuracy, sensitivity, and specificity as evaluation indicators for the classification model.

RESULTS

The model of states at rest had as AUC of 0.82, sensitivity of 75.0%, specificity of 88.9%, and model accuracy of 86.4%. The model of states on exertion had an ACU of 0.82, sensitivity of 83.3%, specificity of 81.3%, and model accuracy of 81.8%.

CONCLUSION

The accuracy of this study's neural network model is comparable to that of previous studies recommended by Japanese Guidelines for the Physical Therapy and is expected to be used in clinical practice. In future, it could be used as a more accurate clinical support tool by increasing the sample size and applying cross-validation.

摘要

目的

我们评估了一种神经网络的准确性,该网络基于新冠病毒病(COVID-19)入院时的患者信息,对出院时家庭氧疗的可能性进行分类和预测。

方法

纳入2020年8月至2021年12月期间在尼崎医疗合作医院接受急性COVID-19治疗后存活的患者。然而,仅纳入了至少经过2周康复期且非通过家庭或机构出院的康复患者(n = 88)。使用患者年龄、性别、聚合酶链反应检测呈阳性与住院之间的天数、住院时间、住院时所需的氧流量以及日常生活活动能力等数据,对在Windows系统的R(4.1.2)中实现的神经网络模型进行训练。训练试验次数为100次。我们将曲线下面积(AUC)、准确率、敏感性和特异性用作分类模型的评估指标。

结果

静息状态模型的AUC为0.82,敏感性为75.0%,特异性为88.9%,模型准确率为86.4%。运动状态模型的ACU为0.82,敏感性为83.3%,特异性为81.3%,模型准确率为81.8%。

结论

本研究神经网络模型的准确性与日本物理治疗指南推荐的先前研究相当,有望用于临床实践。未来,通过增加样本量并应用交叉验证,它可作为更准确的临床支持工具。

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