Mackersie R C, Shackford S R, Hoyt D B, Karagianes T G
Department of Surgery, University of California, San Diego.
J Trauma. 1987 Nov;27(11):1207-12.
The safety and effectiveness of continuous epidural fentanyl analgesia (CEFA) in the treatment of blunt chest injury was evaluated by reviewing its use in 40 patients with multiple rib fractures or flail chest. Ventilatory function tests were performed before and after the institution of CEFA and mean changes calculated. The use of CEFA was associated with significant improvement in vital capacity and maximum inspiratory pressure (p less than 0.05). Minute ventilatory volumes and tidal volumes also showed slight improvement. There was no significant change in arterial CO2 tension with the institution of CEFA, and 85% of patients had good pain relief with CEFA. None of these patients required any other narcotic administration. Documented complications associated with CEFA included pruritus, urinary retention, and transient hypotension. There were no major associated complications. The results suggest that CEFA is a safe, effective method of pain control that acts to improve ventilatory function in patients with blunt chest trauma.
通过回顾连续硬膜外给予芬太尼镇痛(CEFA)在40例多根肋骨骨折或连枷胸患者中的应用情况,评估其治疗钝性胸部损伤的安全性和有效性。在实施CEFA前后进行通气功能测试,并计算平均变化。CEFA的使用与肺活量和最大吸气压力的显著改善相关(p<0.05)。分钟通气量和潮气量也有轻微改善。实施CEFA后动脉二氧化碳分压无显著变化,85%的患者使用CEFA后疼痛得到良好缓解。这些患者均无需使用其他麻醉剂。记录的与CEFA相关的并发症包括瘙痒、尿潴留和短暂性低血压。无重大相关并发症。结果表明,CEFA是一种安全、有效的疼痛控制方法,可改善钝性胸部创伤患者的通气功能。