Suppr超能文献

同期主动脉瓣和肺动脉瓣置换术治疗先天性心脏病术后患者。

Simultaneous Aortic and Pulmonary Valve Replacement in Repaired Congenital Heart Disease.

机构信息

Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany.

Department of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany.

出版信息

Thorac Cardiovasc Surg. 2024 Aug;72(5):358-365. doi: 10.1055/a-2041-3528. Epub 2023 Feb 23.

Abstract

OBJECTIVES

Patients with congenital heart disease frequently require surgical or percutaneous interventional valve replacement after initial congenital heart defect (CHD) repair. In some of these patients, simultaneous replacement of both semilunar valves is necessary, resulting in increased procedural complexity, morbidity, and mortality. In this study, we analyze the outcomes of simultaneous aortic and pulmonary valve replacements following multiple surgical interventions for CHD.

METHODS

This was a retrospective study of 24 patients who after initial repair of CHD underwent single-stage aortic and pulmonary valve replacement at our institution between 2003 and 2021.

RESULTS

The mean age of the patients was 28 ± 13 years; the mean time since the last surgery was 15 ± 11 years. Decellularized valved homografts (DVHs) were used in nine patients, and mechanical valves were implanted in seven others. In eight patients, DVHs, biological, and mechanical valves were implanted in various combinations. The mean cardiopulmonary bypass time was 303 ± 104 minutes, and aortic cross-clamp time was 152 ± 73 minutes. Two patients died at 12 and 16 days postoperatively. At a maximum follow-up time of 17 years (mean 7 ± 5 years), 95% of the surviving patients were categorized as New York Heart Association heart failure class I.

CONCLUSION

Single-stage aortic and pulmonary valve replacement after initial repair of CHD remains challenging with substantial perioperative mortality (8.3%). Nevertheless, long-term survival and clinical status at the latest follow-up were excellent. The valve type had no relevant impact on the postoperative course. The selection of the valves for implantation should take into account operation-specific factors-in particular reoperability-as well as the patients' wishes.

摘要

目的

先天性心脏病(CHD)患者在初次心脏缺陷修复后,常需进行外科或经皮介入瓣膜置换。在这些患者中,有些需要同时置换两个半月瓣,这会增加手术的复杂性、发病率和死亡率。本研究分析了在多次 CHD 手术干预后,同期行主动脉瓣和肺动脉瓣置换的结果。

方法

这是一项回顾性研究,纳入了 2003 年至 2021 年期间,在我院初次 CHD 修复后,行同期主动脉瓣和肺动脉瓣置换的 24 例患者。

结果

患者的平均年龄为 28 ± 13 岁,末次手术至本次手术的平均时间为 15 ± 11 年。9 例患者使用去细胞瓣膜同种移植物(DVH),7 例患者植入机械瓣膜。8 例患者中,不同组合植入了 DVH、生物瓣膜和机械瓣膜。体外循环时间平均为 303 ± 104 分钟,主动脉阻断时间为 152 ± 73 分钟。2 例患者术后 12 天和 16 天死亡。在 17 年的最大随访时间(平均 7 ± 5 年)内,95%的存活患者被归类为纽约心脏协会心功能分级 I 级。

结论

CHD 初次修复后同期行主动脉瓣和肺动脉瓣置换仍然具有挑战性,围手术期死亡率较高(8.3%)。然而,长期存活率和最近的随访时的临床状态极好。瓣膜类型对术后病程无显著影响。植入瓣膜的选择应考虑到手术的具体因素,特别是再手术能力,以及患者的意愿。

相似文献

2
Limited versus full sternotomy for aortic valve replacement.主动脉瓣置换术的有限胸骨切开术与全胸骨切开术对比
Cochrane Database Syst Rev. 2017 Apr 10;4(4):CD011793. doi: 10.1002/14651858.CD011793.pub2.
8
A Meta-Analysis of Sutureless or Rapid-Deployment Aortic Valve Replacement.无缝合或快速植入主动脉瓣置换术的荟萃分析
Thorac Cardiovasc Surg. 2016 Aug;64(5):400-9. doi: 10.1055/s-0035-1566130. Epub 2015 Nov 25.
10
Should we use mechanical valves in patients with end-stage renal disease?我们应该在终末期肾病患者中使用机械瓣膜吗?
Interact Cardiovasc Thorac Surg. 2012 Aug;15(2):240-3. doi: 10.1093/icvts/ivs115. Epub 2012 May 2.

本文引用的文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验