Saad Antonio, Safarzadeh Melody, Shepherd Megan
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555, USA.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555, USA.
Obstet Gynecol Clin North Am. 2023 Mar;50(1):241-249. doi: 10.1016/j.ogc.2022.10.010.
This article explores current recommendations for anticoagulation therapy in pregnancy, including antepartum, intrapartum, and postpartum guidelines. The authors review various screening strategies used to assess whether a patient is an appropriate candidate for anticoagulation during pregnancy and the postpartum period. The article includes dosing regimens, optimal surveillance, and medication reversal. The authors also address the challenges of transitioning between low-molecular-weight heparin and unfractionated heparin. Finally, there is a discussion of intrapartum anticoagulation management, especially as it relates to the administration of regional anesthesia, and the indications for and timing of thromboprophylaxis following delivery.
本文探讨了妊娠期抗凝治疗的当前建议，包括产前、产时和产后指南。作者回顾了用于评估患者是否适合在妊娠期和产后进行抗凝治疗的各种筛查策略。文章包括给药方案、最佳监测和药物逆转。作者还讨论了在低分子量肝素和普通肝素之间转换的挑战。最后，讨论了产时抗凝管理，特别是与区域麻醉的给药相关的内容，以及分娩后血栓预防的指征和时机。
