Han Jennie, Lalario Andrea, Merro Enzo, Sinagra Gianfranco, Sharma Sanjay, Papadakis Michael, Finocchiaro Gherardo
Department of Cardiology, Royal Brompton Hospital, London SW3 6NP, UK.
Department of Cardiology, Azienda Sanitaria Universitaria Integrata Giuliano Isontina (ASUGI), University of Trieste, 34123 Trieste, Italy.
J Cardiovasc Dev Dis. 2023 Feb 5;10(2):68. doi: 10.3390/jcdd10020068.
The benefits of exercise for cardiovascular and general health are many. However, sudden cardiac death (SCD) may occur in apparently healthy athletes who perform at the highest levels. A diverse spectrum of diseases is implicated in SCD in athletes, and while atherosclerotic coronary artery disease predominates in individuals of >35 years of age, primary cardiomyopathies and ion channelopathies are prevalent in young individuals. Prevention of SCD in athletes relies on the implementation of health policies aimed at the early identification of arrhythmogenic diseases (such as cardiac screening) and successful resuscitation (such as widespread utilization of automatic external defibrillators and training members of the public on cardiopulmonary resuscitation). This review will focus on the epidemiology and aetiologies of SCD in athletes, and examine fallacies in the approach to this controversial field. Furthermore, potential strategies to prevent these tragic events will be discussed, analysing current practice, gaps in knowledge and future directions.
运动对心血管和整体健康有诸多益处。然而,在表现最为出色的看似健康的运动员中,可能会发生心源性猝死(SCD)。运动员发生SCD涉及多种疾病,虽然动脉粥样硬化性冠状动脉疾病在35岁以上人群中占主导,但原发性心肌病和离子通道病在年轻人中更为普遍。预防运动员发生SCD依赖于实施旨在早期识别致心律失常疾病(如心脏筛查)和成功复苏(如广泛使用自动体外除颤器以及培训公众进行心肺复苏)的健康政策。本综述将聚焦于运动员SCD的流行病学和病因,并审视这一有争议领域的研究误区。此外,还将讨论预防这些悲剧事件的潜在策略,分析当前的做法、知识空白和未来方向。