School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China.
College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Mar Drugs. 2023 Feb 11;21(2):120. doi: 10.3390/md21020120.
Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine. A growing body of evidence demonstrates that marine organisms are prolific sources of depsipeptides, such as marine cyanobacteria, sponges, mollusks, microorganisms and algae. However, these substances have not yet been comprehensively summarized. In order to enrich our knowledge about marine depsipeptides, their biological sources and structural features, as well as bioactivities, are highlighted in this review after an extensive literature search and data analysis.
深海肤肽是一类重要的多肽，其由通过酰胺键和酯键连接的羟基酸和氨基酸残基组成，在农业和医学领域具有广泛的应用前景。越来越多的证据表明，海洋生物是深海肤肽的丰富来源，如海洋蓝藻、海绵、软体动物、微生物和藻类。然而，这些物质尚未得到全面总结。为了丰富我们对海洋深海肤肽的认识，本文在广泛的文献检索和数据分析的基础上，重点介绍了其生物来源、结构特征和生物活性。
