Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
Department of Population of Health Economics, Dehradun Institute of Technology, Uttarakhand, India.
Curr Probl Cardiol. 2023 Jul;48(7):101666. doi: 10.1016/j.cpcardiol.2023.101666. Epub 2023 Feb 23.
A considerable epidemiological and pathogenetic overlap exists between tuberculosis (TB) and cardiovascular diseases (CVD). The objective of this study was to establish the prevalence of CVD in the TB population. A systematic literature search was performed using Scopus, PubMed, EBSCO, ProQuest, Web of Science on January 25, 2023 using the keywords: "Tuberculosis," "TB," "mycobacterium tuberculosis," and "cardiovascular disease," "CVD" and with individual terms of various CVDs. Observational Studies were included if they reported the prevalence of CVD in the presence of TB in an adult population. The Newcastle-Ottawa Scale was used for quality evaluation. Statistical analyses were performed using STATA version 17. From 10 studies involving 46715 TB patients, a combined prevalence of CVDs was found to be 11% (CI: 95%, 5-16) with significant heterogeneity across studies (I = 96.72%). This study showed a considerable prevalence of CVD among TB patients suggesting TB patients to consider cardiac examination.
结核病（TB）和心血管疾病（CVD）之间存在相当大的流行病学和发病机制重叠。本研究的目的是确定结核病人群中心血管疾病的患病率。使用 Scopus、PubMed、EBSCO、ProQuest、Web of Science 于 2023 年 1 月 25 日进行了系统的文献检索，使用的关键词是：“Tuberculosis”、“TB”、“mycobacterium tuberculosis”和“cardiovascular disease”、“CVD”以及各种 CVD 的单独术语。如果观察性研究报告了在成人人群中存在结核病时 CVD 的患病率，则将其纳入。使用纽卡斯尔-渥太华量表进行质量评估。使用 STATA 版本 17 进行统计分析。从涉及 46715 例结核病患者的 10 项研究中，发现 CVD 的综合患病率为 11%（CI：95%，5-16），各研究之间存在显著异质性（I=96.72%）。本研究表明结核病患者中 CVD 的患病率相当高，这表明结核病患者需要考虑进行心脏检查。
