Castenholz A
Department of Human Biology, University of Kassel, Federal Republic of Germany.
Lymphology. 1987 Sep;20(3):112-25.
The luminal and outer wall morphology of the initial lymphatics in the rat tongue were demonstrated using scanning electron microscopy (SEM) after tissue perfusion with pressures up to 300 torr, topical heat and histamine administration. The findings emphasize the structural and functional importance of the reticular fiber network of the basement lamina (in contradistinction to single "anchoring filaments") as a supportive framework for lymphatic endothelium and a major regulatory role in tissue volume control. Increased tissue pressure was associated with dilatation of initial lymphatics which was maximal at approximately 60 torr. Higher pressures (up to 300 torr) did not damage the vessels. This vasodilatory response of the initial lymphatics was even more evident when tissue swelling was hindered by externally applied plaster "bandage". Under SEM, protruding and branched cells were conspicuous in otherwise flat lymphatic endothelium. These cells may have contractile properties and with pronounced dilatation, thermal injury and application of histamine these cells probably contract, thereby creating large gaps at the site of open junctions.
在对大鼠舌部组织施加高达300托的压力进行灌注、局部加热并给予组胺后，使用扫描电子显微镜（SEM）对大鼠舌部初始淋巴管的管腔和外壁形态进行了观察。研究结果强调了基膜网状纤维网络（与单一“锚定丝”不同）作为淋巴管内皮细胞的支持框架以及在组织体积控制中的主要调节作用的结构和功能重要性。组织压力升高与初始淋巴管扩张有关，在约60托时扩张最大。更高的压力（高达300托）并未损伤血管。当外用石膏“绷带”阻碍组织肿胀时，初始淋巴管的这种血管舒张反应更为明显。在扫描电子显微镜下，在原本扁平的淋巴管内皮中，突出且分支的细胞很明显。这些细胞可能具有收缩特性，在明显扩张、热损伤和应用组胺时，这些细胞可能会收缩，从而在开放连接部位形成大的间隙。
