Kalauzi Aleksandar, Matić Zoran, Platiša Mirjana M, Bojić Tijana
Department for Life Sciences, Institute for Multidisciplinary Research, University of Belgrade, 11030 Belgrade, Serbia.
Biomedical Engineering and Technologies, University of Belgrade, 11000 Belgrade, Serbia.
Bioengineering (Basel). 2023 Jan 31;10(2):180. doi: 10.3390/bioengineering10020180.
Due to the fact that respiratory breath-to-breath and cardiac intervals between two successive R peaks ( and , respectively) are not temporally concurrent, in a previous paper, we proposed a method to calculate both the integer and non-integer parts of the pulse respiration quotient ( = / = + + ), and being parts of the border for each . In this work, we study the correlations between and , as well as those between and mean within each (), on a group of twenty subjects in four conditions: in supine and standing positions, in combination with spontaneous and slow breathing. Results show that the vs. correlations are positive; whereas the breathing regime had little or no effect on the linear regression slopes, body posture did. Two types of scatter plots were obtained with the vs. correlations: one showed points aggregated around the concurrent lines, while the other showed randomly distributed points. Five out of six of the proposed aggregation measures confirmed the existence of these two cardio-respiratory coupling regimes. We also used to study the positions of R pulses relative to the respiration onsets and showed that they were more synchronous with sympathetic activation. Overall, this method should be used in different pathological states.
由于连续两个R波峰之间的呼吸逐次呼吸间隔和心脏间隔（分别为 和 ）在时间上不同步，在之前的一篇论文中，我们提出了一种计算脉搏呼吸商整数和非整数部分的方法（ = / = + + ），其中 和 是每个 的边界部分。在这项工作中，我们研究了一组20名受试者在四种条件下 的相关性，以及每个 内 的相关性，这四种条件为：仰卧位和站立位，结合自主呼吸和慢呼吸。结果表明， 与 的相关性为正；呼吸方式对线性回归斜率影响很小或没有影响，而身体姿势有影响。 与 的相关性得到了两种类型的散点图：一种显示点聚集在同步 线周围，而另一种显示点随机分布。所提出的六种聚集度量中的五种证实了这两种心肺耦合机制的存在。我们还使用 研究了R波相对于呼吸起始的位置，并表明它们与交感神经激活更同步。总体而言，该方法应用于不同的病理状态。
