Meliț Lorena Elena, Dincă Andreea Ligia, Borka Balas Reka, Mocanu Simona, Mărginean Cristina Oana
Department of Pediatrics I, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, Gheorghe Marinescu Street No 38, 540136 Târgu Mureș, Romania.
Department of Pathology, County Emergency Hospital Târgu Mureș, Gheorghe Marinescu Street No 50, 540136 Târgu Mureș, Romania.
Children (Basel). 2023 Jan 28;10(2):229. doi: 10.3390/children10020229.
infection is one of the main causes of dyspepsia, but it is not the only cause. Esophageal inlet patches are areas of heterotopic gastric mucosa within the esophagus and are commonly located in the cervical part of the esophagus. We report the case of a 16-year-old female, previously known to display symptoms of anxiety, who was admitted to our clinic for dyspeptic symptoms lasting for approximately 1 month in spite of the treatment with proton pump inhibitors. The clinical exam revealed only abdominal tenderness in the epigastric area, while routine laboratory tests showed no abnormalities. The upper digestive endoscopy revealed a well-circumscribed salmon-pink-colored oval lesion of approximately 10 mm in the cervical esophagus, along with hyperemia of the gastric mucosa and biliary reflux. The histopathological exam established the diagnosis of esophageal inlet patch with heterotopic antral-type gastric mucosa and also revealed regenerative changes within the gastric mucosa. We continued to treat the patient with proton pump inhibitors, as well as ursodeoxycholic acid, with favorable evolution. Although rare or underdiagnosed, esophageal inlet patches should never be underestimated and all gastroenterologists should be aware of their presence when performing an upper digestive examination in a patient with dyspeptic symptoms.
感染是消化不良的主要原因之一,但并非唯一原因。食管入口斑是食管内异位胃黏膜区域,通常位于食管颈部。我们报告一例16岁女性病例,该患者既往有焦虑症状,尽管使用质子泵抑制剂治疗,但仍因消化不良症状持续约1个月而入住我院。临床检查仅发现上腹部压痛,而常规实验室检查未发现异常。上消化道内镜检查发现食管颈部有一个边界清晰的鲑鱼粉红色椭圆形病变,大小约10毫米,同时伴有胃黏膜充血和胆汁反流。组织病理学检查确诊为食管入口斑伴异位胃窦型胃黏膜,还发现胃黏膜有再生性改变。我们继续用质子泵抑制剂以及熊去氧胆酸治疗该患者,病情好转。尽管食管入口斑罕见或诊断不足,但绝不应被低估,所有胃肠病学家在对有消化不良症状的患者进行上消化道检查时都应意识到其存在。