Choi Iee-Ho, Yeom Sang-Woo, Kim Sun-Young, You Jihye, Kim Jong-Seung, Kim Minsun
Department of Pediatrics, Jeonbuk National University Medical School, Jeonju 54896, Republic of Korea.
Department of Otolaryngology-Head and Neck Surgery, Jeonbuk National University Medical School, Jeonju 54896, Republic of Korea.
Children (Basel). 2023 Feb 10;10(2):358. doi: 10.3390/children10020358.
We examined the associations of clinical characteristics and cause-of-death patterns with mortality in children and young adults (<30 years) with diabetes. We analyzed a nationwide cohort sample from the KNHIS database using propensity score matching from a sample of 1 million people from 2002 to 2013. There were 10,006 individuals in the diabetes mellitus (DM) group and 10,006 in the control (no DM) group. The numbers of deaths were 77 in the DM group and 20 in the control group. The deaths of patients in the DM Group were 3.74 (95% confidence interval (CI) = 2.25-6.21) times higher than in the control group. Type 1 DM, type 2 DM and unspecified DM were 4.52 (95% CI = 1.89-10.82) times, 3.25 (95% CI = 1.95-5.43) times and 10.20 (95% CI = 5.24-20.18) times higher, respectively. Mental disorders were 2.08 times higher in the risk of death (95% CI = 1.27-3.40). Mortality rates have increased in children and young adults with diabetes alone. Therefore, in the future, it is necessary to identify the cause of the increased mortality rate among young diabetic people and select vulnerable groups among them so that early prevention can be achieved.
我们研究了糖尿病儿童和青年（<30岁）的临床特征及死因模式与死亡率之间的关联。我们使用倾向得分匹配法，对韩国国民健康保险服务（KNHIS）数据库中2002年至2013年的100万人全国队列样本进行了分析。糖尿病（DM）组有10,006人，对照组（无DM）有10,006人。DM组死亡77人，对照组死亡20人。DM组患者的死亡人数比对照组高3.74倍（95%置信区间（CI）=2.25 - 6.21）。1型糖尿病、2型糖尿病和未分类糖尿病分别高4.52倍（95% CI = 1.89 - 10.82）、3.25倍（95% CI = 1.95 - 5.43）和10.20倍（95% CI = 5.24 - 20.18）。精神障碍患者的死亡风险高2.08倍（95% CI = 1.27 - 3.40）。仅患有糖尿病的儿童和青年的死亡率有所上升。因此，未来有必要确定年轻糖尿病患者死亡率上升的原因，并在其中挑选出弱势群体，以便实现早期预防。
