Guo Hang, Yu Leilei, Tian Fengwei, Chen Wei, Zhai Qixiao
State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Foods. 2023 Feb 5;12(4):692. doi: 10.3390/foods12040692.
Inflammatory bowel disease (IBD) is a heterogeneous group of diseases associated with chronic inflammation of the intestinal tract, and is highly prevalent worldwide. Although its origin is not yet fully understood, new evidence emphasizes that environmental factors, especially dietary factors and intestinal microbiota disorders are key triggers of IBD. Probiotics, such as spp., play an essential role in human health as they exert beneficial effects on the composition of the human gastrointestinal microbial community and immune system. Probiotic-based therapies have been shown to be effective in alleviating IBD. Among these, is one of the most widely used strains. is widely present in the intestines of healthy individuals; it regulates the intestinal immune system and reduces inflammation through a variety of mechanisms. The purpose of this study was to identify scientific evidence related to and IBD, review and summarize the results, and discuss the possible mechanisms of action as a starting point for future research on IBD treatment.
炎症性肠病(IBD)是一组与肠道慢性炎症相关的异质性疾病,在全球范围内高度流行。尽管其病因尚未完全明确,但新证据强调环境因素,尤其是饮食因素和肠道微生物群紊乱是IBD的关键触发因素。益生菌,如 属,对人类健康起着至关重要的作用,因为它们对人类胃肠道微生物群落的组成和免疫系统发挥有益作用。基于益生菌的疗法已被证明对缓解IBD有效。其中, 是使用最广泛的菌株之一。 在健康个体的肠道中广泛存在;它通过多种机制调节肠道免疫系统并减轻炎症。本研究的目的是识别与 和IBD相关的科学证据,回顾和总结结果,并讨论可能的作用机制,作为未来IBD治疗研究的起点。