Department of Otolaryngology, Phoniatrics and Audiology, Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.
Department of Immunology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, 87-100 Torun, Poland.
Int J Environ Res Public Health. 2023 Feb 7;20(4):2910. doi: 10.3390/ijerph20042910.
The aim of this study was to compare adenoid size in preschool-age siblings using flexible nasopharyngoscopy examination (FNE) when they reach the same age. The occurrence of adenoid symptoms in these patients was also analyzed. This study was conducted to analyze the adenoid size in siblings when they reach the same age and substantiate a correlation between adenoid hypertrophy (AH) and adenoid symptoms.
We analyzed and reported on the symptoms, ENT examination results, and FNE of 49 pairs of siblings who were examined at the same age.
There was a strong association in adenoid size between siblings when they are at a similar age (r = 0.673, < 0.001). Second-born children whose older sibling had III AH (A/C ratio > 65%) had a risk of III AH 26 times greater than patients whose older sibling did not have III AH (OR = 26.30, 95% CI = 2.82-245.54). Over 90% of snoring children whose siblings had confirmed III AH would develop III AH by the time they reach the same age. Second-born children in whom snoring occurs and whose older siblings have a III AH have about a 46 times higher risk of III AH compared to patients who did not meet these two conditions ( < 0.001, OR = 46.67, 95% CI = 8.37-260.30).
A significant familial correlation between adenoid size in siblings when they reach the same age was shown. If the older sibling has a confirmed overgrown adenoid (III AH) and their younger sibling presents adenoid symptoms, particularly snoring, it is highly probable that they will also have an overgrown adenoid.
本研究旨在比较年龄相同时使用软式鼻咽镜检查（FNE）的学龄前兄弟姐妹的腺样体大小。还分析了这些患者腺样体症状的发生情况。进行这项研究是为了分析年龄相同时的兄弟姐妹的腺样体大小，并证实腺样体肥大（AH）与腺样体症状之间存在相关性。
我们分析并报告了 49 对在相同年龄接受检查的兄弟姐妹的症状、耳鼻喉科检查结果和 FNE。
年龄相同时，兄弟姐妹的腺样体大小存在很强的相关性（r = 0.673，<0.001）。有较大腺样体（A/C 比值>65%）的哥哥或姐姐的二胎儿童患 III 度 AH 的风险比哥哥或姐姐没有 III 度 AH 的儿童高 26 倍（OR = 26.30，95%CI = 2.82-245.54）。超过 90%的有明确 III 度 AH 的打鼾儿童在达到相同年龄时会发展为 III 度 AH。在有打鼾且其哥哥或姐姐有 III 度 AH 的二胎儿童中，患 III 度 AH 的风险比没有满足这两种条件的患者高约 46 倍（<0.001，OR = 46.67，95%CI = 8.37-260.30）。
显示了年龄相同时兄弟姐妹的腺样体大小之间存在显著的家族相关性。如果年龄较大的兄弟姐妹被确诊为腺样体过度生长（III 度 AH），且他们的弟弟或妹妹有腺样体症状，特别是打鼾，那么他们很可能也有腺样体过度生长。
