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单次远程缺血预处理和行走对久坐老年人群的潜在益处:一项初步研究。

Potential Benefits of a Single Session of Remote Ischemic Preconditioning and Walking in Sedentary Older Adults: A Pilot Study.

机构信息

Research Unit in Clinical Biomechanics (UBIC), Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, 46010 Valencia, Spain.

Strength Training and Neuromuscular Performance Research Group (STreNgthP), Faculty of Health, Camilo José Cela University, 28692 Madrid, Spain.

出版信息

Int J Environ Res Public Health. 2023 Feb 16;20(4):3515. doi: 10.3390/ijerph20043515.

DOI:10.3390/ijerph20043515
PMID:36834210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9966602/
Abstract

Ischemic preconditioning (IPC) has shown positive effects in endurance-type sports among healthy young individuals; however, its effects in endurance-type exercises in older adults have not been explored. We aimed to examine the acute effects of a single session of IPC prior to an endurance-type exercise on cardiovascular- and physical-function-related parameters in sedentary older adults. A pilot study with a time-series design was carried out. Nine participants were enrolled consecutively in the following intervention groups: (i) SHAM (sham IPC + walking) and (ii) IPC (IPC + walking) groups. The main outcomes were resting systolic (SBP) and diastolic (DBP) blood pressure, heart rate (HR), peripheral oxygen saturation (SpO), maximum isometric voluntary contraction (MIVC), endurance performance, and perceived fatigue. After the intervention, the IPC group showed a significant reduction in SBP, whereas SpO decreased in the SHAM group. The IPC group maintained quadriceps MIVC levels, whereas these levels dropped in the SHAM group. No changes in DBP, resting HR, endurance, or fatigue in any group were observed. These findings are of interest for the promotion of cardiovascular and physical health in older people.

摘要

缺血预处理 (IPC) 在健康年轻个体的耐力型运动中显示出积极的效果;然而,其在老年耐力型运动中的效果尚未得到探索。我们旨在研究单次 IPC 预处理对久坐老年个体耐力型运动相关心血管和身体功能参数的急性影响。采用时间序列设计进行了一项初步研究。连续纳入了 9 名参与者,分为以下干预组:(i)SHAM(假 IPC+行走)和(ii)IPC(IPC+行走)组。主要结局为静息收缩压(SBP)和舒张压(DBP)、心率(HR)、外周血氧饱和度(SpO)、最大等长随意收缩(MIVC)、耐力表现和疲劳感。干预后,IPC 组 SBP 显著降低,而 SHAM 组 SpO 降低。IPC 组股四头肌 MIVC 水平保持不变,而 SHAM 组则下降。任何组的 DBP、静息 HR、耐力或疲劳均未发生变化。这些发现对促进老年人的心血管和身体健康具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51f8/9966602/dd9f2c53345e/ijerph-20-03515-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51f8/9966602/dd9f2c53345e/ijerph-20-03515-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51f8/9966602/dd9f2c53345e/ijerph-20-03515-g001.jpg

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本文引用的文献

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Ischemic Preconditioning Improves Handgrip Strength and Functional Capacity in Active Elderly Women.缺血预处理可提高活跃老年女性的握力和功能能力。
Int J Environ Res Public Health. 2022 May 29;19(11):6628. doi: 10.3390/ijerph19116628.
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2021 ESC Guidelines on cardiovascular disease prevention in clinical practice.2021年欧洲心脏病学会临床实践中心血管疾病预防指南。
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Methodological Variations Contributing to Heterogenous Ergogenic Responses to Ischemic Preconditioning.
导致对缺血预处理产生不同运动能力增强反应的方法学差异。
Front Physiol. 2021 Apr 29;12:656980. doi: 10.3389/fphys.2021.656980. eCollection 2021.
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Int J Cardiol Hypertens. 2021 Feb 23;8:100081. doi: 10.1016/j.ijchy.2021.100081. eCollection 2021 Mar.
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Effect of remote ischaemic preconditioning on walking in people with multiple sclerosis: double-blind randomised controlled trial.远程缺血预处理对多发性硬化症患者步行能力的影响:双盲随机对照试验。
BMJ Neurol Open. 2020 Mar 23;2(1):e000022. doi: 10.1136/bmjno-2019-000022. eCollection 2020.
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A multicentre prospective observational study comparing arterial blood gas values to those obtained by pulse oximeters used in adult patients attending Australian and New Zealand hospitals.一项多中心前瞻性观察研究,比较了在澳大利亚和新西兰医院就诊的成年患者使用脉搏血氧仪获得的动脉血气值与那些值。
BMC Pulm Med. 2020 Jan 9;20(1):7. doi: 10.1186/s12890-019-1007-3.
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Hypertension in older adults: Assessment, management, and challenges.老年人高血压:评估、管理与挑战。
Clin Cardiol. 2020 Feb;43(2):99-107. doi: 10.1002/clc.23303. Epub 2019 Dec 11.
8
An overview of ischemic preconditioning in exercise performance: A systematic review.运动表现中缺血预处理的综述:一项系统评价。
J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.
9
Two weeks of ischemic conditioning improves walking speed and reduces neuromuscular fatigability in chronic stroke survivors.两周的缺血性预处理可改善慢性脑卒中幸存者的步行速度并降低神经肌肉疲劳性。
J Appl Physiol (1985). 2019 Mar 1;126(3):755-763. doi: 10.1152/japplphysiol.00772.2018. Epub 2019 Jan 17.
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Eur J Appl Physiol. 2018 Dec;118(12):2541-2549. doi: 10.1007/s00421-018-3979-8. Epub 2018 Oct 25.