Olney R K, Budingen H J, Miller R G
Department of Neurology, Veterans Administration Medical Center, Portland, Oregon.
Muscle Nerve. 1987 Oct;10(8):728-33. doi: 10.1002/mus.880100809.
In 32 ulnar nerves of healthy volunteers, the mean area of the compound muscle action potential recorded over abductor digiti minimi was reduced by 7.4% when comparing above-elbow with wrist stimulation and by 1.9% when comparing above-elbow with below-elbow stimulation. In 20 of these nerves, the mean area of the compound nerve action potential (CNAP) recorded over the fifth digit was reduced by 36% when comparing above-elbow with wrist stimulation. Area reduction of the compound action potential, especially of the CNAP, appears to be a characteristic effect of temporal dispersion in peripheral nerve when utilizing the bipolar recording technique routinely employed in clinical neurophysiology. A thorough understanding of the effects caused by temporal dispersion and of their quantitative limits in normal peripheral nerve is important for the proper interpretation of nerve conduction studies.
在32名健康志愿者的尺神经中，当比较肘部以上与腕部刺激时，小指展肌记录的复合肌肉动作电位平均面积减少了7.4%，当比较肘部以上与肘部以下刺激时，减少了1.9%。在其中20条神经中，当比较肘部以上与腕部刺激时，第五指记录的复合神经动作电位（CNAP）平均面积减少了36%。复合动作电位的面积减少，尤其是CNAP的面积减少，似乎是在临床神经生理学中常规使用的双极记录技术时外周神经中时间离散的一个特征性效应。全面了解时间离散所引起的效应及其在正常外周神经中的定量限度，对于正确解释神经传导研究很重要。
