Department of Public Health, Faculty of Applied Medical Sciences, Albaha University, Albaha 65779, Saudi Arabia.
Int J Environ Res Public Health. 2023 Feb 20;20(4):3767. doi: 10.3390/ijerph20043767.
Consanguineous marriage (CM) is a prevalent kind of relationship in Muslim and Arab countries, and this type of relationship is linked to several health risks. This study was conducted to determine the prevalence of (CM), its associated hereditary diseases, and health-related issues among Saudi citizens in Albaha. This cross-sectional study was conducted between March 2021 to April 2021. Saudi citizens in Albaha who were aged ≥ 18 years and willing to participate were eligible for the study. A total of 1010 participants were included in this study. In total, 757 participants were married, widowed, or divorced. CM partnerships comprised 40% ( = 302) of the marriages among participants, of which first- and second-cousin marriages comprised 72% and 28%, respectively. The prevalence of CM among the participants' parents was lower than that among the participants (31% versus 40%, respectively). Children of participants in a CM were more likely to have cardiovascular diseases ( < 0.001), blood diseases (anaemia, thalassemia) ( < 0.001), cancer ( = 0.046), hearing loss and speech disorder ( = 0.003), and ophthalmic diseases ( = 0.037). Albaha showed a high percentage of consanguinity. An educational program must be established to enhance the population's knowledge of the consequences of CM. The current national premarital screening program should be extended to involve more screening tests for common hereditary diseases that result from CM.
近亲婚姻(CM)在穆斯林和阿拉伯国家很普遍,这种关系与多种健康风险有关。本研究旨在确定沙特阿拉伯阿巴哈地区公民中 CM 的流行率、相关遗传疾病以及与健康相关的问题。这是一项横断面研究,于 2021 年 3 月至 2021 年 4 月进行。年龄≥18 岁且愿意参加的沙特阿拉伯阿巴哈公民有资格参加这项研究。本研究共纳入 1010 名参与者。共有 757 名参与者已婚、丧偶或离婚。CM 伴侣占参与者婚姻的 40%(=302),其中第一和第二代表亲婚姻分别占 72%和 28%。参与者父母的 CM 发生率低于参与者(分别为 31%和 40%)。参与者的 CM 子女更有可能患有心血管疾病(<0.001)、血液疾病(贫血、地中海贫血)(<0.001)、癌症(=0.046)、听力损失和言语障碍(=0.003)和眼科疾病(=0.037)。阿巴哈表现出很高的近亲结婚率。必须建立一个教育计划,以提高人们对 CM 后果的认识。目前的国家婚前筛查计划应扩大范围,纳入更多由 CM 引起的常见遗传疾病的筛查测试。