Department of Entomology and MOA Key Laboratory of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Int J Mol Sci. 2023 Feb 5;24(4):3138. doi: 10.3390/ijms24043138.
The stability of symbiotic flora is an important indicator of the health of an organism. Symbiotic bacteria have been proven to be closely involved in the immune process of organisms. The pathogenicity of was studied in relation to symbiotic bacteria on the surface and inside of the migratory locust (). The results showed that the surface disinfection of test locusts contributed to the pathogenicity of to locusts. Most of the surface bacteria of caused some inhibition of growth, and LM5-4 (), LM5-2 (), and LM5-13 () showed the highest inhibitory effect on the growth of The inoculation of locusts with additional surface symbiotic bacteria reduced the virulence of to . Infection by different strains of caused similar changes in the symbiotic flora of migratory locusts. The inoculation of locusts with additional intestinal symbiotic bacteria ( sp.) reduced the virulence of to . These findings illustrate the effect of bacterial communities on fungal infections in when seen from the perspective of ecology in a microenvironment. The active antifungal substances of such bacteria and their mechanisms of action need further study.
共生菌群的稳定性是生物体健康的一个重要指标。共生细菌已被证明与生物体的免疫过程密切相关。本研究探讨了()体表和体内共生细菌与蝗灾之间的关系。结果表明,试验蝗虫的体表消毒有助于()对蝗虫的致病性。大多数()表面细菌对()的生长有一定的抑制作用,LM5-4()、LM5-2()和 LM5-13()对()的生长抑制作用最强。向蝗虫接种额外的体表共生细菌会降低()对蝗虫的毒力。不同()菌株的感染导致了东亚飞蝗共生菌群的相似变化。向蝗虫接种额外的肠道共生细菌()会降低()对蝗虫的毒力。这些发现从微环境生态学的角度说明了细菌群落对东亚飞蝗真菌感染的影响。需要进一步研究这些细菌的活性抗真菌物质及其作用机制。