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微调小型非编码 RNA 以改善植物的理想性状。

Tweaking the Small Non-Coding RNAs to Improve Desirable Traits in Plant.

机构信息

National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India.

Centre for Transgenic Plant Development, Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India.

出版信息

Int J Mol Sci. 2023 Feb 5;24(4):3143. doi: 10.3390/ijms24043143.

Abstract

Plant transcriptome contains an enormous amount of non-coding RNAs (ncRNAs) that do not code for proteins but take part in regulating gene expression. Since their discovery in the early 1990s, much research has been conducted to elucidate their function in the gene regulatory network and their involvement in plants' response to biotic/abiotic stresses. Typically, 20-30 nucleotide-long small ncRNAs are a potential target for plant molecular breeders because of their agricultural importance. This review summarizes the current understanding of three major classes of small ncRNAs: short-interfering RNAs (siRNAs), microRNA (miRNA), and transacting siRNAs (tasiRNAs). Furthermore, their biogenesis, mode of action, and how they have been utilized to improve crop productivity and disease resistance are discussed here.

摘要

植物转录组中含有大量不编码蛋白质但参与调控基因表达的非编码 RNA(ncRNA)。自上世纪 90 年代初发现以来,大量研究已经阐明了它们在基因调控网络中的功能及其在植物应对生物/非生物胁迫中的作用。通常,20-30 个核苷酸长的小 ncRNA 因其在农业中的重要性而成为植物分子育种的潜在目标。本综述总结了小 ncRNA 三大类的最新研究进展:短干扰 RNA(siRNA)、微小 RNA(miRNA)和反式作用 siRNA(tasiRNA)。此外,还讨论了它们的生物发生、作用模式以及如何利用它们来提高作物产量和抗病性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f985/9966754/474f196e407a/ijms-24-03143-g001.jpg

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