Wongtangman Thiti, Thatphet Phraewa, Shokoohi Hamid, McFadden Kathleen, Ma Irene, Al Saud Ahad, Vivian Rachel, Hines Ryan, Gullikson Jamie, Morone Christina, Parente Jason, Perkisas Stany, Liu Shan W
Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Department of Emergency Medicine, Lerdsin General Hospital, Krung Thep Maha Nakhon 10500, Thailand.
J Clin Med. 2023 Feb 4;12(4):1251. doi: 10.3390/jcm12041251.
To determine the association between point-of-care-ultrasonography (POCUS)-measured sarcopenia and grip strength, as well as the history of prior-year falls among older adults admitted to the emergency department observation unit (EDOU).
This cross-sectional observational study was conducted over 8 months at a large urban teaching hospital. A consecutive sample of patients who were 65 years or older and admitted to the EDOU were enrolled in the study. Using standardized techniques, trained research assistants and co-investigators measured patients' biceps brachii and thigh quadriceps muscles via a linear transducer. Grip strength was measured using a Jamar Hydraulic Hand Dynamometer. Participants were surveyed regarding their history of falls in the prior year. Logistic regression analyses assessed the relationship of sarcopenia and grip strength to a history of falls (the primary outcome).
Among 199 participants (55% female), 46% reported falling in the prior year. The median biceps thickness was 2.22 cm with an Interquartile range [IQR] of 1.87-2.74, and the median thigh muscle thickness was 2.91 cm with an IQR of 2.40-3.49. A univariate logistic regression analysis demonstrated a correlation between higher thigh muscle thickness, normal grip strength, and history of prior-year falling, with an odds ratio [OR] of 0.67 (95% conference interval [95%CI] 0.47-0.95) and an OR of 0.51 (95%CI 0.29-0.91), respectively. In multivariate logistic regression, only higher thigh muscle thickness was correlated with a history of prior-year falls, with an OR of 0.59 (95% CI 0.38-0.91).
POCUS-measured thigh muscle thickness has the potential to identify patients who have fallen and thus are at high risk for future falls.
确定在急诊科观察病房(EDOU)住院的老年人中,即时超声检查(POCUS)测量的肌肉减少症与握力以及上一年跌倒史之间的关联。
这项横断面观察性研究在一家大型城市教学医院进行了8个月。连续纳入65岁及以上且入住EDOU的患者样本。使用标准化技术,经过培训的研究助理和共同研究者通过线性换能器测量患者的肱二头肌和股四头肌。使用Jamar液压式握力计测量握力。就参与者上一年的跌倒史进行调查。逻辑回归分析评估肌肉减少症和握力与跌倒史(主要结局)之间的关系。
在199名参与者(55%为女性)中,46%报告上一年有跌倒。肱二头肌厚度中位数为2.22厘米,四分位间距[IQR]为1.87 - 2.74,股四头肌厚度中位数为2.91厘米,IQR为2.40 - 3.49。单因素逻辑回归分析显示,较高的股四头肌厚度、正常握力与上一年跌倒史之间存在相关性,比值比[OR]分别为0.67(95%置信区间[95%CI] 0.47 - 0.95)和0.51(95%CI 0.29 - 0.91)。在多因素逻辑回归中,只有较高的股四头肌厚度与上一年跌倒史相关,OR为0.59(95%CI 0.38 - 0.91)。
POCUS测量的股四头肌厚度有可能识别出过跌倒且因此未来跌倒风险高的患者。