Marcelino Vanessa, De Rovere Solène, Paço Maria, Gonçalves Maria, Marcelino Sandra, Guimarães António Sérgio, Pinho Teresa
UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), 4585-116 Gandra, Portugal.
TOXRUN-Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
Life (Basel). 2023 Feb 8;13(2):472. doi: 10.3390/life13020472.
The literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol in the PubMed, Cochrane Library, LILACS, EBSCO, Scielo, between 2012 and 2022. The methodological quality was assessed by using the Newcastle-Ottawa Study Quality Assessment Scale. Mean differences and 95% confidence intervals were calculated and combined in meta-analyses. A total of 1202 participants were included in this systematic review (690 with TMD; 512 without TMD), with 22 articles being included in the qualitative analysis. Only three studies enabled the comparative analysis of the results. Ten articles showed a high methodological quality and a low risk of bias, and twelve had a low methodological quality and an increased risk of bias. The meta-analysis showed that the differences between the intervention and control groups were not statistically significant for the percentage overlapping coefficient of the anterior temporal muscle, for the masseter, and for the torque coefficient. The parameters analyzed with the compound technique for chewing showed altered mandibular functions in individuals with TMD. With the EMG method, it was possible to suggest that TMD in adult individuals causes compensatory muscle behaviors, and several changes in the masticatory function were found.
根据系统评价和Meta分析的首选报告项目（PRISMA）协议，于2012年至2022年期间在PubMed、Cochrane图书馆、LILACS、EBSCO、Scielo中进行文献检索。采用纽卡斯尔-渥太华研究质量评估量表评估方法学质量。计算平均差异和95%置信区间，并在Meta分析中进行合并。本系统评价共纳入1202名参与者（690名患有颞下颌关节紊乱病；512名未患颞下颌关节紊乱病），定性分析纳入22篇文章。只有三项研究能够对结果进行比较分析。十篇文章显示方法学质量高且偏倚风险低，十二篇文章显示方法学质量低且偏倚风险增加。Meta分析表明，干预组和对照组在前颞肌重叠系数百分比、咬肌和扭矩系数方面的差异无统计学意义。采用复合咀嚼技术分析的参数显示，颞下颌关节紊乱病患者的下颌功能发生改变。通过肌电图方法，可以认为成年个体的颞下颌关节紊乱病会导致代偿性肌肉行为，并发现咀嚼功能有若干变化。
