镍钛形状记忆合金制成的植入物表面功能化

Functionalization of the Implant Surface Made of NiTi Shape Memory Alloy.

作者信息

Dudek Karolina, Goryczka Tomasz, Dulski Mateusz, Psiuk Bronisław, Szurko Agnieszka, Lekston Zdzisław

机构信息

Center of Refractory Materials, Łukasiewicz Research Network-Institute of Ceramics and Building Materials, Toszecka 99, 44-100 Gliwice, Poland.

Institute of Materials Science, Silesian Center for Education and Interdisciplinary Research, University of Silesia in Katowice, 75 Pulku Piechoty 1A, 41-500 Chorzow, Poland.

出版信息

Materials (Basel). 2023 Feb 15;16(4):1609. doi: 10.3390/ma16041609.

DOI:10.3390/ma16041609

PMID:36837239

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9963895/

Abstract

To functionalize and improve the biocompatibility of the surface of a medical implant made of NiTi shape memory alloy and used in practice, a clamp, multifunctional layers composed of amorphous TiO interlayer, and a hydroxyapatite coating were produced. Electrophoresis, as an efficient method of surface modification, resulted in the formation of a uniform coating under a voltage of 60 V and deposition time of 30 s over the entire volume of the implant. The applied heat treatment (800 °C/2 h) let toa dense, crack-free, well-adhered HAp coating with a thickness of ca. 1.5 μm. and a high crack resistance to deformation associated with the induction of the shape memory effect in the in the deformation range similar to the real implant work after implantation. Moreover, the obtained coating featured a hydrophilic (CA = 59.4 ± 0.3°) and high biocompatibility.

摘要

为了使实际应用中的镍钛形状记忆合金制成的医用植入物表面功能化并提高其生物相容性，制备了一种夹具、由非晶TiO中间层组成的多功能层以及羟基磷灰石涂层。电泳作为一种高效的表面改性方法，在60V电压和30s沉积时间下，在植入物的整个表面形成了均匀的涂层。进行的热处理（800°C/2h）得到了致密、无裂纹、附着力良好的HAp涂层，其厚度约为1.5μm，并且在与植入后实际植入物工作相似的变形范围内，具有与形状记忆效应诱导相关的高抗变形裂纹能力。此外，所获得的涂层具有亲水性（接触角CA = 59.4±0.3°）和高生物相容性。