Dudek Karolina, Strach Aleksandra, Wasilkowski Daniel, Łosiewicz Bożena, Kubisztal Julian, Mrozek-Wilczkiewicz Anna, Zioła Patryk, Barylski Adrian
Łukasiewicz Research Network-Institute of Ceramics and Building Materials, Cementowa 8, 31-983 Kraków, Poland.
Doctoral School, University of Silesia, Bankowa 14, 40-032 Katowice, Poland.
J Funct Biomater. 2024 Sep 12;15(9):264. doi: 10.3390/jfb15090264.
To functionalize the NiTi alloy, multifunctional innovative nanocoatings of Ag-TiO and Ag-TiO doped with hydroxyapatite were engineered on its surface. The coatings were thoroughly characterized, focusing on surface topography and key functional properties, including adhesion, surface wettability, biocompatibility, antibacterial activity, and corrosion resistance. The electrochemical corrosion kinetics in a simulated body fluid and the mechanisms were analyzed. The coatings exhibited hydrophilic properties and were biocompatible with fibroblast and osteoblast cells while also demonstrating antibacterial activity against and . The coatings adhered strongly to the NiTi substrate, with superior adhesion observed in the hydroxyapatite-doped layers. Conversely, the Ag-TiO layers showed enhanced corrosion resistance.
为了使镍钛合金功能化,在其表面设计了掺有羟基磷灰石的Ag-TiO和Ag-TiO多功能创新纳米涂层。对涂层进行了全面表征,重点关注表面形貌和关键功能特性,包括附着力、表面润湿性、生物相容性、抗菌活性和耐腐蚀性。分析了模拟体液中的电化学腐蚀动力学及其机制。涂层表现出亲水性,与成纤维细胞和成骨细胞具有生物相容性,同时还对[具体细菌名称1]和[具体细菌名称2]表现出抗菌活性。涂层与镍钛基体牢固结合,在掺有羟基磷灰石的涂层中观察到了优异的附着力。相反,Ag-TiO涂层显示出增强的耐腐蚀性。