Song Fengcheng, Xu Yishu, Peng Peng, Li Hongxu, Zheng Ranxi, Zhang Haolin, Han Yingying, Weng Qiang, Yuan Zhengrong
College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Metabolites. 2023 Feb 9;13(2):248. doi: 10.3390/metabo13020248.
The gut microbiota plays a crucial role in the nutrition, metabolism, and immune function of the host animal. The muskrat () is a typical seasonal breeding animal. The present study performed a metagenomic analysis of cecum contents from muskrats in the breeding and non-breeding seasons. The results indicated that the breeding muskrats and non-breeding muskrats differed in gut microbiota structure and function. During the breeding season, the relative abundance of phylum Bacteroidetes, genus , and genus increased, while the relative abundance of phylum Firmicutes and phylum Actinobacteria decreased. The muskrat gut microbiota was enriched in the metabolism-related pathways, especially amino acid and vitamin metabolism, and genetically related metabolites in the breeding season. We presumed that the muskrat gut microbiota might seasonally change to secure reproductive activity and satisfy the metabolic demands of different seasons. This study could explore potential mechanisms by which gut microbiota affects reproduction. Moreover, this study may provide a new theoretical basis for the management of muskrat captive breeding.
肠道微生物群在宿主动物的营养、代谢和免疫功能中起着至关重要的作用。麝鼠（）是一种典型的季节性繁殖动物。本研究对繁殖季节和非繁殖季节麝鼠的盲肠内容物进行了宏基因组分析。结果表明，繁殖期麝鼠和非繁殖期麝鼠的肠道微生物群在结构和功能上存在差异。在繁殖季节，拟杆菌门、属和属的相对丰度增加，而厚壁菌门和放线菌门的相对丰度降低。麝鼠肠道微生物群在繁殖季节的代谢相关途径中富集，尤其是氨基酸和维生素代谢以及遗传相关代谢产物。我们推测，麝鼠肠道微生物群可能会季节性变化，以确保生殖活动并满足不同季节的代谢需求。本研究可以探索肠道微生物群影响繁殖的潜在机制。此外，本研究可能为麝鼠圈养繁殖管理提供新的理论依据。
