Pan Dequan, Wang Wei, Cheng Tong
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, China.
Microorganisms. 2023 Feb 17;11(2):519. doi: 10.3390/microorganisms11020519.
Infection with the varicella-zoster virus (VZV) causes chickenpox and shingles, which lead to significant morbidity and mortality globally. The detection of serum VZV-specific antibodies is important for the clinical diagnosis and sero-epidemiological research of VZV infection, and for assessing the effect of VZV vaccine immunization. Over recent decades, a variety of methods for VZV antibody detection have been developed. This review summarizes and compares the current methods for detecting VZV antibodies, and discussed future directions for this field.
感染水痘-带状疱疹病毒（VZV）会引发水痘和带状疱疹，在全球范围内导致显著的发病率和死亡率。检测血清中VZV特异性抗体对于VZV感染的临床诊断、血清流行病学研究以及评估VZV疫苗免疫效果都很重要。近几十年来，已开发出多种检测VZV抗体的方法。本文综述并比较了当前检测VZV抗体的方法，并探讨了该领域的未来发展方向。
