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血液传播病原体检测的范式转变:从传统方法到最新检测技术

A paradigm shift in the detection of bloodborne pathogens: conventional approaches to recent detection techniques.

作者信息

Khanal Sonali, Pillai Manjusha, Biswas Deblina, Torequl Islam Muhammad, Verma Rachna, Kuca Kamil, Kumar Dinesh, Najmi Asim, Zoghebi Khalid, Khalid Asaad, Mohan Syam

机构信息

School of Bioengineering and Food Technology, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.

Instrumentation and Control Engineering, Dr. B. R. Ambedkar National Institute of Technology Jalandhar, Punjab, 144011, India.

出版信息

EXCLI J. 2024 Oct 17;23:1245-1275. doi: 10.17179/excli2024-7392. eCollection 2024.

DOI:10.17179/excli2024-7392
PMID:39574968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11579516/
Abstract

Bloodborne pathogens (BBPs) pose formidable challenges in the realm of infectious diseases, representing significant risks to both human and animal health worldwide. The review paper provides a thorough examination of bloodborne pathogens, highlighting the serious worldwide threat they pose and the effects they have on animal and human health. It addresses the potential dangers of exposure that healthcare workers confront, which have affected 3 million people annually, and investigates the many pathways by which these viruses can spread. The limitations of traditional detection techniques like PCR and ELISA have been criticized, which has led to the investigation of new detection methods driven by advances in sensor technology. The objective is to increase the amount of knowledge that is available regarding bloodborne infections as well as effective strategies for their management and detection. This review provides a thorough overview of common bloodborne infections, including their patterns of transmission, and detection techniques.

摘要

血源性病原体(BBPs)在传染病领域构成了巨大挑战,对全球人类和动物健康都构成了重大风险。这篇综述论文对血源性病原体进行了全面审视,强调了它们在全球范围内构成的严重威胁以及对动物和人类健康的影响。它探讨了医护人员面临的暴露潜在危险,每年有300万人受到影响,并研究了这些病毒传播的多种途径。传统检测技术如PCR和ELISA的局限性受到了批评,这促使人们基于传感器技术的进步对新的检测方法进行研究。目的是增加关于血源感染的可用知识以及对其管理和检测的有效策略。本综述全面概述了常见的血源感染,包括它们的传播模式和检测技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92e5/11579516/c7f2562d61b9/EXCLI-23-1245-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92e5/11579516/c7f2562d61b9/EXCLI-23-1245-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92e5/11579516/c7f2562d61b9/EXCLI-23-1245-t-002.jpg

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