Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road Stanford, Stanford, CA 94305, USA.
Oregon Research Institute, Springfield, OR 97477, USA.
Nutrients. 2023 Feb 17;15(4):1008. doi: 10.3390/nu15041008.
: Test whether the efficacy of , an obesity/eating disorder prevention program, is improved by delivering it in single-sex groups and adding food response inhibition and attention training. : High-risk young adults ( = 261; age = 19.3, 74% female) were randomized to (1) single-sex or (2) mixed-sex groups that completed food response inhibition and attention training or (3) single-sex or (4) mixed-sex groups that completed sham training with nonfood images in a 2 × 2 factorial design. : There was a significant sex-composition by training-type by time interaction; participants who completed single- or mixed-sex groups plus food response and attention training showed significant reductions in body fat over a 2-year follow-up, though this effect was more rapid and persistent in single-sex groups, whereas those who completed single- or mixed-sex groups plus sham training did not show body fat change. However, there were no differences in overweight/obesity onset over the follow-up. The manipulated factors did not affect eating disorder symptoms or eating disorder onset, but there was a significant reduction in symptoms across the conditions (within-condition = -0.58), converging with prior evidence that produced larger reductions in symptoms (within-condition = -0.48) than educational control participants. Average eating disorder onset over the 2-year follow-up (6.4%) was similar to that observed in in a past trial (4.5%). : Given that significantly reduced future onset of overweight/obesity in a prior trial and the present trial found that body fat loss effects were significantly greater when implemented in single-sex groups and paired with food response and attention training, there might be value in broadly implementing this combined intervention.
：测试通过在单性别组中进行并添加食物反应抑制和注意力训练，是否能提高肥胖/饮食障碍预防计划的效果。：高危年轻成年人（n=261；年龄=19.3，74%为女性）随机分为（1）单性别或（2）混合性别组，完成食物反应抑制和注意力训练或（3）单性别或（4）混合性别组，完成非食物图像的假训练，采用 2×2 析因设计。：存在性别构成与训练类型与时间的显著交互作用；完成单性别或混合性别组加食物反应和注意力训练的参与者，在 2 年随访期间，体脂显著减少，尽管这种效果在单性别组中更快且更持久，而完成单性别或混合性别组加假训练的参与者则没有体脂变化。然而，在随访期间，超重/肥胖的发生率没有差异。所操纵的因素并未影响饮食障碍症状或饮食障碍的发生，但在所有条件下，症状都有显著减轻（条件内= -0.58），与先前的证据一致，即 比教育对照组产生更大的症状减轻（条件内= -0.48）。在 2 年的随访期间（6.4%），平均饮食障碍发生率与过去一项试验（4.5%）相似。：鉴于 在前一项试验中显著降低了超重/肥胖的未来发生率，而本试验发现，当在单性别组中实施并与食物反应和注意力训练相结合时，体脂损失效果显著更大，因此广泛实施这种联合干预可能具有价值。
