Skowrońska Weronika, Bazylko Agnieszka
Department of Pharmaceutical Biology, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Pharmaceutics. 2023 Feb 13;15(2):633. doi: 10.3390/pharmaceutics15020633.
Treating burns remains a challenge for modern medicine, especially in developing countries that cannot afford expensive, advanced therapies. This review article summarises clinical and animal model studies of botanical preparations and their mixtures in treating burn wounds and sunburn. Articles available in electronic databases such as PubMed, Scopus, Web of Science, Science Direct and Google Scholar, published in English in 2010-2022, were considered. In the described clinical trials, it was shown that some herbal preparations have better effectiveness in treating burn wounds, including shortening the healing time and reducing inflammation, than the conventional treatment used hitherto. These herbal preparations contained extracts from , , , , and , , , , , and mixtures of and . Research on animal models shows that many extracts may potentially benefit the treatment of burn wounds and sunburn. Due to the diverse mechanism of action, antibacterial activity, the safety of use and cost-effectiveness, herbal preparations can compete with conventional treatment. The growing interest in alternative medicine and herbal medicine encourages further research. Not only single preparations but also their mixtures should be taken into account because the research conducted so far often suggests a synergistic effect of the ingredients.
治疗烧伤仍然是现代医学面临的一项挑战,尤其是在那些负担不起昂贵先进疗法的发展中国家。这篇综述文章总结了植物制剂及其混合物在治疗烧伤创面和晒伤方面的临床及动物模型研究。我们考虑了2010年至2022年期间以英文发表在电子数据库(如PubMed、Scopus、Web of Science、Science Direct和谷歌学术)上的文章。在所描述的临床试验中,结果表明,与迄今使用的传统治疗方法相比,一些草药制剂在治疗烧伤创面方面具有更好的效果,包括缩短愈合时间和减轻炎症。这些草药制剂含有来自[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]以及[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]、[此处原文缺失植物名称]的提取物,以及[此处原文缺失植物名称]和[此处原文缺失植物名称]的混合物。动物模型研究表明,许多提取物可能对烧伤创面和晒伤的治疗有潜在益处。由于作用机制多样、具有抗菌活性、使用安全且具有成本效益,草药制剂可以与传统治疗方法相竞争。对替代医学和草药医学日益增长的兴趣鼓励了进一步的研究。不仅单一制剂,而且它们的混合物都应予以考虑,因为迄今为止进行的研究常常表明成分之间具有协同作用。