Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Am J Hum Biol. 2023 Jul;35(7):e23885. doi: 10.1002/ajhb.23885. Epub 2023 Feb 24.
The body mass index (BMI) has some limitations in identifying obesity, particularly among children and adolescents.
We sought to determine the reference percentiles of tri-ponderal mass index (TMI) for Iranian population, and its relation to BMI, waist circumference (WC), and waist circumference-to-height ratio (WHtR).
Baseline characteristics for 14 641 children and adolescents were applied. The area under the characteristics (AUC) curve and optimal cut-off points for TMI were used to define the accuracy of TMI for discriminating general and central obesity compared to other anthropometric measurements.
TMI levels remained stable from 6 to 18 years with a small range of difference. The highest AUCs for discriminating obesity according to BMI and WHtR ≥0.5 from non-obese subjects were related to TMI (0.980) and TMI (0.912), respectively, and these findings were similar for both sexes. Moreover, the AUC for TMI to discriminate central obesity by WHtR was higher than that for BMI (0.912 vs. 0.833, p < .001), and this difference was similar among sex and age groups. The optimal value of TMI for discriminating general obesity, obesity by WC, and obesity by WHtR were 15.2 (sensitivity 96.2 and specificity 89.8), 15 (sensitivity 86.9 and specificity 79.9), and 13.9 (sensitivity 85.1 and specificity 81.5), respectively.
TMI discriminated central obesity by WHtR more accurately than obesity by BMI among Iranian children and adolescents irrespective of sex. Besides it remained relatively constant across age- and sex-specific groups providing a single optimal cut-off point for screening obesity during childhood and adolescence.
体重指数(BMI)在识别肥胖方面存在一些局限性,尤其是在儿童和青少年中。
我们旨在确定伊朗人群的三部位体质量指数(TMI)参考百分位数,并研究其与 BMI、腰围(WC)和腰围身高比(WHtR)的关系。
对 14641 名儿童和青少年的基线特征进行了应用。使用特征曲线下面积(AUC)和 TMI 的最佳截断点来定义 TMI 在区分一般肥胖和中心性肥胖方面与其他人体测量学测量值的准确性。
TMI 水平在 6 至 18 岁之间保持稳定,差异范围较小。用于区分 BMI 和 WHtR≥0.5 定义的肥胖与非肥胖个体的 AUC 值最高的是 TMI(0.980)和 TMI(0.912),这些发现与性别无关。此外,TMI 用于区分 WHtR 定义的中心性肥胖的 AUC 高于 BMI(0.912 与 0.833,p<0.001),且在性别和年龄组之间差异相似。TMI 用于区分一般肥胖、WC 定义的肥胖和 WHtR 定义的肥胖的最佳值分别为 15.2(敏感性 96.2,特异性 89.8)、15(敏感性 86.9,特异性 79.9)和 13.9(敏感性 85.1,特异性 81.5)。
TMI 比 BMI 更能准确地识别伊朗儿童和青少年的 WHtR 定义的中心性肥胖,与性别无关。此外,它在年龄和性别特定组中相对保持不变,为儿童和青少年时期筛查肥胖提供了单一的最佳截断点。