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不良童年经历和慢性健康状况对当前抑郁的影响。

Effects of Adverse Childhood Experiences and Chronic Health Conditions on Current Depression.

机构信息

University of Southern Mississippi, School of Psychology, Owings-McQuagge Hall 231, 118 College Dr., #5025, Hattiesburg, MS, 39406, United States.

Department of Psychology, Auburn University at Montgomery, 7430 East Drive, Montgomery, AL, 36117, United States.

出版信息

Community Ment Health J. 2023 Aug;59(6):1208-1216. doi: 10.1007/s10597-023-01103-3. Epub 2023 Feb 25.

DOI:10.1007/s10597-023-01103-3
PMID:36840804
Abstract

This study investigated the ability of three adverse childhood experience (ACE) types (household dysfunction, emotional/physical abuse, and sexual abuse) to predict current depression among adults. We also determined the contribution of ACEs to current depression after controlling for covariates and chronic illnesses. Respondents to the 2010 Behavioral Risk Factor Surveillance System (n = 20,345) were divided into depressed and not depressed groups based on Patient Health Questionnaire-8 (PHQ-8) scores. Binary logistic regression determined the ability of ACE exposure to predict depression while controlling for effects of covariates and number of chronic illnesses. Hierarchical multiple linear regression determined the association of ACEs on depression scores after accounting for the covariate set and chronic illnesses. Sexual Abuse had the single strongest association with current depression of any ACE exposure. Exposure to three ACE types has the greatest association with current depression. ACEs accounted for about 7% of the variance in depression scores.

摘要

这项研究调查了三种不良童年经历(ACE)类型(家庭功能障碍、情感/身体虐待和性虐待)对成年人当前抑郁状况的预测能力。我们还确定了 ACE 在控制协变量和慢性疾病后对当前抑郁的贡献。根据患者健康问卷-8(PHQ-8)评分,将 2010 年行为风险因素监测系统(n=20345)的受访者分为抑郁组和非抑郁组。二元逻辑回归确定了 ACE 暴露预测抑郁的能力,同时控制了协变量和慢性疾病数量的影响。分层多元线性回归确定了 ACE 对抑郁评分的关联,同时考虑了协变量集和慢性疾病。性虐待与任何 ACE 暴露的当前抑郁状况具有最强的单一关联。三种 ACE 类型的暴露与当前抑郁的关联最大。ACE 占抑郁评分差异的 7%左右。

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本文引用的文献

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JAMA Psychiatry. 2019 Jun 1;76(6):584-593. doi: 10.1001/jamapsychiatry.2019.0097.
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The Relation Between Adverse Childhood Experiences and Adult Health: Turning Gold into Lead.童年不良经历与成人健康之间的关系:化金为铅。
Perm J. 2002 Winter;6(1):44-47. doi: 10.7812/TPP/02.994.
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Associations Between Adverse Childhood Experiences, High-Risk Behaviors, and Morbidity in Adulthood.
童年不良经历、高危行为与成年期发病之间的关联。
Am J Prev Med. 2016 Mar;50(3):344-352. doi: 10.1016/j.amepre.2015.07.022. Epub 2015 Oct 21.
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The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.由于共同的遗传效应,较低的教育程度与抑郁症之间的关联?对约25000名受试者的研究结果。
Mol Psychiatry. 2015 Jun;20(6):735-43. doi: 10.1038/mp.2015.50. Epub 2015 Apr 28.
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The mediating role of emotion dysregulation and depression on the relationship between childhood trauma exposure and emotional eating.情绪调节障碍和抑郁在童年创伤暴露与情绪化进食关系中的中介作用。
Appetite. 2015 Aug;91:129-36. doi: 10.1016/j.appet.2015.03.036. Epub 2015 Apr 9.
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